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10.1111/ajt.13521 http://scihub22266oqcxt.onion/10.1111/ajt.13521 C4996417!4996417!26595644     free     free     free Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Am+J+Transplant 2016 ; 16 (3): 808-20 Nephropedia Template TP {{tp|p=26595644|t=2016. Exogenous Lipocalin 2 Ameliorates Acute Rejection in a Mouse Model of Renal Transplantation |pdf=|usr=}}{{26595644}} gab.com Text Exogenous Lipocalin 2 Ameliorates Acute Rejection in a Mouse Model of Renal Transplantation JO: Am J Transplant http://www.kidney.de/pget.php?&tw=1&pmid=26595644 #FOAvip Lipocalin 2 (Lcn2) is rapidly produced by damaged nephron epithelia and is one of the most promising new markers of renal injury, delayed graft function and acute allograft rejection (AR); however, the functional importance of Lcn2 in renal transplantation is largely unknown. To understand the role of Lcn2 in renal AR, kidneys from Balb/c mice were transplanted into C57Bl/6 mice and vice versa and analyzed for morphological and physiological outcomes of AR at posttransplantation days 3, 5, and 7. The allografts showed a steady increase in intensity of interstitial infiltration, tubulitis and periarterial aggregation of lymphocytes associated with a substantial elevation in serum levels of creatinine, urea and Lcn2. Perioperative administration of recombinant Lcn2:siderophore:Fe complex (rLcn2) to recipients resulted in functional and morphological amelioration of the allograft at day 7 almost as efficiently as daily immunosuppression with cyclosporine A (CsA). No significant differences were observed in various donor?recipient combinations (C57Bl/6 wild?type and Lcn2?/?, Balb/c donors and recipients). Histochemical analyses of the allografts showed reduced cell death in recipients treated with rLcn2 or CsA. These results demonstrate that Lcn2 plays an important role in reducing the extent of kidney AR and indicate the therapeutic potential of Lcn2 in transplantation. Twit Text FOAVip Exogenous Lipocalin 2 Ameliorates Acute Rejection in a Mouse Model of Renal Transplantation ????Am J Transplant http://www.kidney.de/pget.php?&tw=1&pmid=26595644 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26595644 #FOAvip English Wikipedia <ref>{{Cite pmid|26595644}}</ref> Exogenous Lipocalin 2 Ameliorates Acute Rejection in a Mouse Model of Renal Transplantation #MMPMID26595644 Ashraf MI; Schwelberger HG; Brendel KA; Feurle J; Andrassy J; Kotsch K; Regele H; Pratschke J; Maier HT; Aigner F Am J Transplant 2016[Mar]; 16 (3): 808-20 PMID26595644show ga Lipocalin 2 (Lcn2) is rapidly produced by damaged nephron epithelia and is one of the most promising new markers of renal injury, delayed graft function and acute allograft rejection (AR); however, the functional importance of Lcn2 in renal transplantation is largely unknown. To understand the role of Lcn2 in renal AR, kidneys from Balb/c mice were transplanted into C57Bl/6 mice and vice versa and analyzed for morphological and physiological outcomes of AR at posttransplantation days 3, 5, and 7. The allografts showed a steady increase in intensity of interstitial infiltration, tubulitis and periarterial aggregation of lymphocytes associated with a substantial elevation in serum levels of creatinine, urea and Lcn2. Perioperative administration of recombinant Lcn2:siderophore:Fe complex (rLcn2) to recipients resulted in functional and morphological amelioration of the allograft at day 7 almost as efficiently as daily immunosuppression with cyclosporine A (CsA). No significant differences were observed in various donor?recipient combinations (C57Bl/6 wild?type and Lcn2?/?, Balb/c donors and recipients). Histochemical analyses of the allografts showed reduced cell death in recipients treated with rLcn2 or CsA. These results demonstrate that Lcn2 plays an important role in reducing the extent of kidney AR and indicate the therapeutic potential of Lcn2 in transplantation. äExogenous Lipocalin 2 Ameliorates Acute Rejection in a Mouse Model of (epmc).pdf DeepDyve Pubget Overpricing