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2015 ; 4
(4
): 570-95
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English Wikipedia
Efficient SNP Discovery by Combining Microarray and Lab-on-a-Chip Data for Animal
Breeding and Selection
#MMPMID27600241
Huang CW
; Lin YT
; Ding ST
; Lo LL
; Wang PH
; Lin EC
; Liu FW
; Lu YW
Microarrays (Basel)
2015[Nov]; 4
(4
): 570-95
PMID27600241
show ga
The genetic markers associated with economic traits have been widely explored for
animal breeding. Among these markers, single-nucleotide polymorphism (SNPs) are
gradually becoming a prevalent and effective evaluation tool. Since SNPs only
focus on the genetic sequences of interest, it thereby reduces the evaluation
time and cost. Compared to traditional approaches, SNP genotyping techniques
incorporate informative genetic background, improve the breeding prediction
accuracy and acquiesce breeding quality on the farm. This article therefore
reviews the typical procedures of animal breeding using SNPs and the current
status of related techniques. The associated SNP information and genotyping
techniques, including microarray and Lab-on-a-Chip based platforms, along with
their potential are highlighted. Examples in pig and poultry with different SNP
loci linked to high economic trait values are given. The recommendations for
utilizing SNP genotyping in nimal breeding are summarized.