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10.1093/cvr/cvw175 http://scihub22266oqcxt.onion/10.1093/cvr/cvw175 C4996263!4996263!27357637     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Cardiovasc+Res 2016 ; 111 (4): 310-21 Nephropedia Template TP {{tp|p=27357637|t=2016. Heterogeneity in the lymphatic vascular system and its origin |pdf=|usr=}}{{27357637}} gab.com Text Heterogeneity in the lymphatic vascular system and its origin JO: Cardiovasc Res http://www.kidney.de/pget.php?&tw=1&pmid=27357637 #FOAvip Lymphatic vessels have historically been viewed as passive conduits for fluid and immune cells, but this perspective is increasingly being revised as new functions of lymphatic vessels are revealed. Emerging evidence shows that lymphatic endothelium takes an active part in immune regulation both by antigen presentation and expression of immunomodulatory genes. In addition, lymphatic vessels play an important role in uptake of dietary fat and clearance of cholesterol from peripheral tissues, and they have been implicated in obesity and arteriosclerosis. Lymphatic vessels within different organs and in different physiological and pathological processes show a remarkable plasticity and heterogeneity, reflecting their functional specialization. In addition, lymphatic endothelial cells (LECs) of different organs were recently shown to have alternative developmental origins, which may contribute to the development of the diverse lymphatic vessel and endothelial functions seen in the adult. Here, we discuss recent developments in the understanding of heterogeneity within the lymphatic system considering the organ-specific functional and molecular specialization of LECs and their developmental origin. Twit Text FOAVip Heterogeneity in the lymphatic vascular system and its origin ????Cardiovasc Res http://www.kidney.de/pget.php?&tw=1&pmid=27357637 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27357637 #FOAvip English Wikipedia <ref>{{Cite pmid|27357637}}</ref> Heterogeneity in the lymphatic vascular system and its origin #MMPMID27357637 Ulvmar MH; Mäkinen T Cardiovasc Res 2016[Sep]; 111 (4): 310-21 PMID27357637show ga Lymphatic vessels have historically been viewed as passive conduits for fluid and immune cells, but this perspective is increasingly being revised as new functions of lymphatic vessels are revealed. Emerging evidence shows that lymphatic endothelium takes an active part in immune regulation both by antigen presentation and expression of immunomodulatory genes. In addition, lymphatic vessels play an important role in uptake of dietary fat and clearance of cholesterol from peripheral tissues, and they have been implicated in obesity and arteriosclerosis. Lymphatic vessels within different organs and in different physiological and pathological processes show a remarkable plasticity and heterogeneity, reflecting their functional specialization. In addition, lymphatic endothelial cells (LECs) of different organs were recently shown to have alternative developmental origins, which may contribute to the development of the diverse lymphatic vessel and endothelial functions seen in the adult. Here, we discuss recent developments in the understanding of heterogeneity within the lymphatic system considering the organ-specific functional and molecular specialization of LECs and their developmental origin. äHeterogeneity in the lymphatic vascular system and its origin (epmc).pdf DeepDyve Pubget Overpricing