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10.1002/mrd.22634

http://scihub22266oqcxt.onion/10.1002/mrd.22634
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C4993202!4993202!26970099
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suck abstract from ncbi


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pmid26970099      Mol+Reprod+Dev 2016 ; 83 (5): 376-86
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  • The molecular complexity of fertilization: Introducing the concept of a fertilization synapse #MMPMID26970099
  • Krauchunas A; Marcello M; Singson A
  • Mol Reprod Dev 2016[May]; 83 (5): 376-86 PMID26970099show ga
  • The details of sperm-egg interactions remain a relative mystery despite many decades of research. As new molecular complexities are being discovered, we need to revise the framework in which we think about fertilization. As such, we propose that fertilization involves the formation of a synapse between the sperm and egg. A cellular synapse is a structure that mediates cell adhesion, signaling, and secretion through specialized zones of interaction and polarity. In this review, we draw parallels between the immune synapse and fertilization and argue that we should consider sperm-egg recognition, binding, and fusion in the context of a ?fertilization synapse?.
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