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Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Acta+Neurol+Belg 2016 ; 116 (ä): 259-69 Nephropedia Template TP
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Detection superiority of 7 T MRI protocol in patients with epilepsy and suspected focal cortical dysplasia #MMPMID27389578
Colon AJ; van Osch MJP; Buijs M; Grond Jvd; Boon P; van Buchem MA; Hofman PAM
Acta Neurol Belg 2016[]; 116 (ä): 259-69 PMID27389578show ga
In 11 adult patients with suspicion of Focal cortical dysplasia (FCD) on 1.5 T (n = 1) or 3 T (n = 10) magnetic resonance imaging (MRI), 7 T MRI was performed. Visibility, extent, morphological features and delineation were independently rated and subsequently discussed by three observers. Additionally, head-to-head comparisons with corresponding 3 T images were made in the eight patients with a previous 3 T MRI and sustained suspicion of FCD. Comparison with histopathology was done in the five patients that underwent surgery. All lesions, seen at 1.5 and 3 T, were also recognized on 7 T. At 7 T FLAIR highlighted the FCD-like lesions best, whereas T2 and T2* were deemed better suited to review structure and extent of the lesion. Image quality with the used 7 T MRI setup was higher than the quality with the used 3 T MRI setup. In 2 out of 11 patients diagnosis changed, in one after re-evaluation of the images, and in the other based on histopathology. With the used 7 T MRI setup, FCD-like lesions can be detected with more confidence and detail as compared to lower field strength. However, concordance between radiologic diagnosis and final diagnosis seems to be lower than expected.Electronic supplementary material: The online version of this article (doi:10.1007/s13760-016-0662-x) contains supplementary material, which is available to authorized users.