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10.1016/j.ccm.2016.04.016 http://scihub22266oqcxt.onion/10.1016/j.ccm.2016.04.016 C4987538!4987538!27514600     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=27514600&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       Clin+Chest+Med 2016 ; 37 (3): 557-67 Nephropedia Template TP {{tp|p=27514600|t=2016. Hyper IgE Syndromes and the Lung |pdf=|usr=}}{{27514600}} gab.com Text Hyper IgE Syndromes and the Lung JO: Clin Chest Med http://www.kidney.de/pget.php?&tw=1&pmid=27514600 #FOAvip Elevated serum IgE has many etiologies including parasitic infection, allergy and asthma, malignancy and immune dysregulation. The hyper IgE syndromes due to mutations in STAT3, DOCK8 and PGM3 are monogenic primary immunodeficiencies that are associated with high IgE, eczema and recurrent infections. All of these primary immunodeficiencies are associated with recurrent pneumonias leading to bronchiectasis; however each has unique features and genetic diagnosis is essential in guiding therapy, discussing family planning and defining prognosis. STAT3 mutated HIES is unique with respect to its multi-organ features and frequent pneumatocele formation. DOCK8 deficiency is characterized by severe cutaneous viral infections and early mortality. PGM3 deficiency is newly defined and is distinct in having neurologic abnormalities and cytopenias. Twit Text FOAVip Hyper IgE Syndromes and the Lung ????Clin Chest Med http://www.kidney.de/pget.php?&tw=1&pmid=27514600 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27514600 #FOAvip English Wikipedia <ref>{{Cite pmid|27514600}}</ref> Hyper IgE Syndromes and the Lung #MMPMID27514600 Freeman AF; Olivier KN Clin Chest Med 2016[Sep]; 37 (3): 557-67 PMID27514600show ga Elevated serum IgE has many etiologies including parasitic infection, allergy and asthma, malignancy and immune dysregulation. The hyper IgE syndromes due to mutations in STAT3, DOCK8 and PGM3 are monogenic primary immunodeficiencies that are associated with high IgE, eczema and recurrent infections. All of these primary immunodeficiencies are associated with recurrent pneumonias leading to bronchiectasis; however each has unique features and genetic diagnosis is essential in guiding therapy, discussing family planning and defining prognosis. STAT3 mutated HIES is unique with respect to its multi-organ features and frequent pneumatocele formation. DOCK8 deficiency is characterized by severe cutaneous viral infections and early mortality. PGM3 deficiency is newly defined and is distinct in having neurologic abnormalities and cytopenias. äHyper IgE Syndromes and the Lung (epmc).pdf DeepDyve Pubget Overpricing