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10.1093/jamia/ocv046

http://scihub22266oqcxt.onion/10.1093/jamia/ocv046
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C4986668!4986668!26041386
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suck abstract from ncbi


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pmid26041386      J+Am+Med+Inform+Assoc 2015 ; 22 (5): 1042-53
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  • Birth month affects lifetime disease risk: a phenome-wide method #MMPMID26041386
  • Boland MR; Shahn Z; Madigan D; Hripcsak G; Tatonetti NP
  • J Am Med Inform Assoc 2015[Sep]; 22 (5): 1042-53 PMID26041386show ga
  • Objective An individual?s birth month has a significant impact on the diseases they develop during their lifetime. Previous studies reveal relationships between birth month and several diseases including atherothrombosis, asthma, attention deficit hyperactivity disorder, and myopia, leaving most diseases completely unexplored. This retrospective population study systematically explores the relationship between seasonal affects at birth and lifetime disease risk for 1688 conditions.Methods We developed a hypothesis-free method that minimizes publication and disease selection biases by systematically investigating disease-birth month patterns across all conditions. Our dataset includes 1 749 400 individuals with records at New York-Presbyterian/Columbia University Medical Center born between 1900 and 2000 inclusive. We modeled associations between birth month and 1688 diseases using logistic regression. Significance was tested using a chi-squared test with multiplicity correction.Results We found 55 diseases that were significantly dependent on birth month. Of these 19 were previously reported in the literature (P?
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