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10.1080/21541264.2016.1182240

http://scihub22266oqcxt.onion/10.1080/21541264.2016.1182240
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C4984681!4984681!27115204
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suck abstract from ncbi


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pmid27115204      Transcription 2016 ; 7 (3): 91-5
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  • Transcription-induced DNA supercoiling: New roles of intranucleosomal DNA loops in DNA repair and transcription #MMPMID27115204
  • Gerasimova NS; Pestov NA; Kulaeva OI; Clark DJ; Studitsky VM
  • Transcription 2016[May]; 7 (3): 91-5 PMID27115204show ga
  • RNA polymerase II (Pol II) transcription through chromatin is accompanied by formation of small intranucleosomal DNA loops. Pol II captured within a small loop drives accumulation of DNA supercoiling, facilitating further transcription. DNA breaks relieve supercoiling and induce Pol II arrest, allowing detection of DNA damage hidden in chromatin structure.
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