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10.1073/pnas.1604266113

http://scihub22266oqcxt.onion/10.1073/pnas.1604266113
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C4983805!4983805!27071132
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suck abstract from ncbi


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pmid27071132      Proc+Natl+Acad+Sci+U+S+A 2016 ; 113 (18): 5071-6
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  • Dysregulation of a family of short noncoding RNAs, tsRNAs, in human cancer #MMPMID27071132
  • Pekarsky Y; Balatti V; Palamarchuk A; Rizzotto L; Veneziano D; Nigita G; Rassenti LZ; Pass HI; Kipps TJ; Liu Cg; Croce CM
  • Proc Natl Acad Sci U S A 2016[May]; 113 (18): 5071-6 PMID27071132show ga
  • Chronic lymphocytic leukemia (CLL) is the most common human leukemia. We identified two members of the tRNA-derived small RNA (tsRNA) family, ts-3676 and ts-4521, both inactivated in CLL and lung cancer. We further analyzed expression of 120 tsRNAs and found that tsRNAs are dysregulated in CLL and lung cancer. Thus this study uncovers the involvement of this recently identified class of small, non-coding RNAs in hematopoietic malignancies and solid tumors.
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