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10.1080/23262133.2015.1057313 http://scihub22266oqcxt.onion/10.1080/23262133.2015.1057313 C4973611!4973611 !27606327     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\27606327 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Neurogenesis+(Austin) 2015 ; 2 (1 ): e1057313 Nephropedia Template TP {{tp|p=27606327 |t=2015. Dissecting the role of Wnt signaling and its interactions with FGF signaling during midbrain neurogenesis |pdf=|usr=}}{{27606327 }} gab.com Text Dissecting the role of Wnt signaling and its interactions with FGF signaling during midbrain neurogenesis JO: Neurogenesis (Austin) http://www.kidney.de/pget.php?&tw=1&pmid=27606327 #FOAvip Interactions between FGF and Wnt/ bcat signaling control development of the midbrain. The nature of this interaction and how these regulate patterning, growth and differentiation is less clear, as it has not been possible to temporally dissect the effects of one pathway relative to the other. We have employed pharmacological and genetic tools to probe the temporal and spatial roles of FGF and Wnt in controlling the specification of early midbrain neurons. We identify a ?-catenin (bcat) independent role for GSK-3 in modulating FGF activity and hence neuronal patterning. This function is complicated by an overlap with bcat-dependent regulation of FGF signaling, through the regulation of sprouty4. Additionally we reveal how attenuation of Axin protein function can promote fluctuating levels of bcat activity that are dependent on FGF activity. This highlights the complex nature of the interactions between FGF and Wnt/ bcat and reveals that they act at multiple levels to control each others activity in the midbrain. Twit Text FOAVip Dissecting the role of Wnt signaling and its interactions with FGF signaling during midbrain neurogenesis ????Neurogenesis (Austin) http://www.kidney.de/pget.php?&tw=1&pmid=27606327 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27606327 #FOAvip English Wikipedia <ref>{{Cite pmid|27606327 }}</ref> Dissecting the role of Wnt signaling and its interactions with FGF signaling during midbrain neurogenesis #MMPMID27606327 Dyer C ; Blanc E ; Stanley RJ ; Knight RD Neurogenesis (Austin) 2015[]; 2 (1 ): e1057313 PMID27606327 show ga Interactions between FGF and Wnt/ bcat signaling control development of the midbrain. The nature of this interaction and how these regulate patterning, growth and differentiation is less clear, as it has not been possible to temporally dissect the effects of one pathway relative to the other. We have employed pharmacological and genetic tools to probe the temporal and spatial roles of FGF and Wnt in controlling the specification of early midbrain neurons. We identify a ?-catenin (bcat) independent role for GSK-3 in modulating FGF activity and hence neuronal patterning. This function is complicated by an overlap with bcat-dependent regulation of FGF signaling, through the regulation of sprouty4. Additionally we reveal how attenuation of Axin protein function can promote fluctuating levels of bcat activity that are dependent on FGF activity. This highlights the complex nature of the interactions between FGF and Wnt/ bcat and reveals that they act at multiple levels to control each others activity in the midbrain. äDissecting the role of Wnt signaling and its interactions with FGF sig(epmc).pdf DeepDyve Pubget Overpricing