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10.1080/23723556.2016.1175538

http://scihub22266oqcxt.onion/10.1080/23723556.2016.1175538
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C4972106!4972106!27652323
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suck abstract from ncbi


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pmid27652323      Mol+Cell+Oncol 2016 ; 3 (4): ä
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  • HMGB1: The metabolic weapon in the arsenal of NK cells #MMPMID27652323
  • Cerwenka A; Kopitz J; Schirmacher P; Roth W; Gdynia G
  • Mol Cell Oncol 2016[Jul]; 3 (4): ä PMID27652323show ga
  • Targeting tumor glycolysis would hit the main energy source of cancer. We show that natural killer (NK) cells pursue this strategy by employing high mobility group box 1 (HMGB1) protein?a well-known proinflammatory cytokine?to specifically target glycolysis in cancer cells. This opens up new perspectives for cancer immunotherapy.
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