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10.1152/ajpheart.00572.2015

http://scihub22266oqcxt.onion/10.1152/ajpheart.00572.2015
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C4967198!4967198!27208163
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suck abstract from ncbi

pmid27208163      Am+J+Physiol+Heart+Circ+Physiol 2016 ; 311 (1): H286-98
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  • Purinergic dysregulation in pulmonary hypertension #MMPMID27208163
  • Visovatti SH; Hyman MC; Goonewardena SN; Anyanwu AC; Kanthi Y; Robichaud P; Wang J; Petrovic-Djergovic D; Rattan R; Burant CF; Pinsky DJ
  • Am J Physiol Heart Circ Physiol 2016[Jul]; 311 (1): H286-98 PMID27208163show ga
  • This is the first study to report that deletion of CD39 results in high pulmonary arterial pressures and increases in the intravascular ATP/adenosine ratio and pulmonary vascular P2X1 receptors. It also shows that reconstitution of ectonucleotidase activity lessens, and P2X1 receptor blocking eliminates, elevated pulmonary arterial pressures.
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