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10.1097/BOR.0000000000000318 http://scihub22266oqcxt.onion/10.1097/BOR.0000000000000318 C4965307!4965307!27428889     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Curr+Opin+Rheumatol 2016 ; 28 (5): 497-505 Nephropedia Template TP {{tp|p=27428889|t=2016. Environmental Exposures and the Development of Systemic Lupus Erythematosus |pdf=|usr=}}{{27428889}} gab.com Text Environmental Exposures and the Development of Systemic Lupus Erythematosus JO: Curr Opin Rheumatol http://www.kidney.de/pget.php?&tw=1&pmid=27428889 #FOAvip Purpose of Review: This review examines evidence relating environmental factors to the development of systemic lupus erythematosus (SLE). Recent findings: The strongest epidemiologic evidence exists for the associations of silica, cigarette smoking, oral contraceptives, postmenopausal hormone therapy, and endometriosis, with SLE incidence. Recent studies have also provided robust evidence of the association between alcohol consumption and decreased SLE risk. There are preliminary, conflicting or unsubstantiated data that other factors, including air pollution, ultraviolet light, infections, vaccinations, solvents, pesticides, and heavy metals such as mercury, are related to SLE risk. Biologic mechanisms linking environmental exposures and SLE risk include increased oxidative stress, systemic inflammation and inflammatory cytokine upregulation, and hormonal triggers, as well as epigenetic modifications resulting from exposure that could lead to SLE. Summary: Identifying the environmental risk factors related to risk of SLE is essential as it will lead to increased understanding of pathogenesis of this complex disease and will also make risk factor modification possible for those at increased risk. Twit Text FOAVip Environmental Exposures and the Development of Systemic Lupus Erythematosus ????Curr Opin Rheumatol http://www.kidney.de/pget.php?&tw=1&pmid=27428889 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27428889 #FOAvip English Wikipedia <ref>{{Cite pmid|27428889}}</ref> Environmental Exposures and the Development of Systemic Lupus Erythematosus #MMPMID27428889 Barbhaiya M; Costenbader KH Curr Opin Rheumatol 2016[Sep]; 28 (5): 497-505 PMID27428889show ga Purpose of Review: This review examines evidence relating environmental factors to the development of systemic lupus erythematosus (SLE). Recent findings: The strongest epidemiologic evidence exists for the associations of silica, cigarette smoking, oral contraceptives, postmenopausal hormone therapy, and endometriosis, with SLE incidence. Recent studies have also provided robust evidence of the association between alcohol consumption and decreased SLE risk. There are preliminary, conflicting or unsubstantiated data that other factors, including air pollution, ultraviolet light, infections, vaccinations, solvents, pesticides, and heavy metals such as mercury, are related to SLE risk. Biologic mechanisms linking environmental exposures and SLE risk include increased oxidative stress, systemic inflammation and inflammatory cytokine upregulation, and hormonal triggers, as well as epigenetic modifications resulting from exposure that could lead to SLE. Summary: Identifying the environmental risk factors related to risk of SLE is essential as it will lead to increased understanding of pathogenesis of this complex disease and will also make risk factor modification possible for those at increased risk. äEnvironmental Exposures and the Development of Systemic Lupus Erythema(epmc).pdf DeepDyve Pubget Overpricing