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10.1080/15476286.2016.1181254 http://scihub22266oqcxt.onion/10.1080/15476286.2016.1181254 C4962805!4962805!27128603     free     free     free       RNA+Biol 2016 ; 13 (6): 545-53 Nephropedia Template TP {{tp|p=27128603|t=2016. 7SKiing on chromatin: Move globally, act locally |pdf=|usr=}}{{27128603}} gab.com Text 7SKiing on chromatin: Move globally, act locally JO: RNA Biol http://www.kidney.de/pget.php?&tw=1&pmid=27128603 #FOAvip RNA polymerase II (Pol II) pausing at promoter-proximal regions is a highly regulated step in the transcription cycle. Pause release is facilitated by the P-TEFb kinase, which phosphorylates Pol II and negative elongation factors. Recent studies suggest that P-TEFb (as part of the inhibitory 7SK snRNP) is recruited to promoter-proximal regions through interaction with KAP1/TRIM28/TIF1? to facilitate ?on-site? kinase activation and transcription elongation. Here, I discuss features of this model and future challenges to further hone our understanding of transcriptional regulation including Pol II pausing and pause release. Twit Text FOAVip 7SKiing on chromatin: Move globally, act locally ????RNA Biol http://www.kidney.de/pget.php?&tw=1&pmid=27128603 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27128603 #FOAvip English Wikipedia <ref>{{Cite pmid|27128603}}</ref> 7SKiing on chromatin: Move globally, act locally #MMPMID27128603 D'Orso I RNA Biol 2016[Jun]; 13 (6): 545-53 PMID27128603show ga RNA polymerase II (Pol II) pausing at promoter-proximal regions is a highly regulated step in the transcription cycle. Pause release is facilitated by the P-TEFb kinase, which phosphorylates Pol II and negative elongation factors. Recent studies suggest that P-TEFb (as part of the inhibitory 7SK snRNP) is recruited to promoter-proximal regions through interaction with KAP1/TRIM28/TIF1? to facilitate ?on-site? kinase activation and transcription elongation. Here, I discuss features of this model and future challenges to further hone our understanding of transcriptional regulation including Pol II pausing and pause release. ä7SKiing on chromatin: Move globally, act locally (epmc).pdf DeepDyve Pubget Overpricing