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10.1093/ecco-jcc/jjv196 http://scihub22266oqcxt.onion/10.1093/ecco-jcc/jjv196 C4957465!4957465!26507861     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Crohns+Colitis 2016 ; 10 (3): 354-62 Nephropedia Template TP {{tp|p=26507861|t=2016. Contrast-enhanced Ultrasound for Detection of Crohn?s Disease Activity: Systematic Review and Meta-analysis |pdf=|usr=}}{{26507861}} gab.com Text Contrast-enhanced Ultrasound for Detection of Crohn s Disease Activity: Systematic Review and Meta-analysis JO: J Crohns Colitis http://www.kidney.de/pget.php?&tw=1&pmid=26507861 #FOAvip Background and Aims: : Reports on imaging of active Crohn?s disease (aCD) using contrast-enhanced ultrasound (CEUS) are encouraging. However, the statistical power of most published papers is limited due to the small size of the patient groups included. This study was performed to verify the diagnostic value of CEUS in detecting aCD. Methods: : A systematic literature search was performed by two independent reviewers for articles on the test characteristics of CEUS for the identification of aCD. The quality of the analysed studies was evaluated using a quality assessment tool for diagnostic accuracy studies (QUADAS-2). Pooling was performed using a diagnostic random-effect model and bivariate analysis. Results: : Eight articles were included in the final analysis, with a total of 332 patients. There was no significant publication bias. Significant heterogeneity was found regarding CEUS methodology and sonographic definitions of aCD. In a bivariate analysis, pooled sensitivity was 0.94 (95% CI 0.87?0.97) and pooled specificity was 0.79 (95% CI 0.67?0.88). Spearman correlation statistics presented no significant diagnostic threshold effect (r = 0.12, p > 0.9). Subgroup analysis showed that relative intestine wall enhancement had the highest diagnostic value (area under the curve 94%), while the presence of enhancement and analysis of the slope were less useful (area under the curve 91 and 90%, respectively). Conclusions: : CEUS presents good sensitivity and moderate specificity in the detection of the aCD. Large-scale randomized trials with quantitative evaluation of CEUS images are necessary to promote this technique in clinical practice. Twit Text FOAVip Contrast-enhanced Ultrasound for Detection of Crohn s Disease Activity: Systematic Review and Meta-analysis ????J Crohns Colitis http://www.kidney.de/pget.php?&tw=1&pmid=26507861 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26507861 #FOAvip English Wikipedia <ref>{{Cite pmid|26507861}}</ref> Contrast-enhanced Ultrasound for Detection of Crohn?s Disease Activity: Systematic Review and Meta-analysis #MMPMID26507861 Serafin Z; Bia?ecki M; Bia?ecka A; Sconfienza LM; K?opocka M J Crohns Colitis 2016[Mar]; 10 (3): 354-62 PMID26507861show ga Background and Aims: : Reports on imaging of active Crohn?s disease (aCD) using contrast-enhanced ultrasound (CEUS) are encouraging. However, the statistical power of most published papers is limited due to the small size of the patient groups included. This study was performed to verify the diagnostic value of CEUS in detecting aCD. Methods: : A systematic literature search was performed by two independent reviewers for articles on the test characteristics of CEUS for the identification of aCD. The quality of the analysed studies was evaluated using a quality assessment tool for diagnostic accuracy studies (QUADAS-2). Pooling was performed using a diagnostic random-effect model and bivariate analysis. Results: : Eight articles were included in the final analysis, with a total of 332 patients. There was no significant publication bias. Significant heterogeneity was found regarding CEUS methodology and sonographic definitions of aCD. In a bivariate analysis, pooled sensitivity was 0.94 (95% CI 0.87?0.97) and pooled specificity was 0.79 (95% CI 0.67?0.88). Spearman correlation statistics presented no significant diagnostic threshold effect (r = 0.12, p > 0.9). Subgroup analysis showed that relative intestine wall enhancement had the highest diagnostic value (area under the curve 94%), while the presence of enhancement and analysis of the slope were less useful (area under the curve 91 and 90%, respectively). Conclusions: : CEUS presents good sensitivity and moderate specificity in the detection of the aCD. Large-scale randomized trials with quantitative evaluation of CEUS images are necessary to promote this technique in clinical practice. äContrast-enhanced Ultrasound for Detection of Crohn?s Disease Activity(epmc).pdf DeepDyve Pubget Overpricing