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10.1016/j.artd.2015.03.003

http://scihub22266oqcxt.onion/10.1016/j.artd.2015.03.003
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C4956685!4956685!28326376
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suck abstract from ncbi

pmid28326376      Arthroplasty+Today 2015 ; 1 (3): 77-80
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  • Total knee arthroplasty in ochronosis #MMPMID28326376
  • Patel VG
  • Arthroplasty Today 2015[Sep]; 1 (3): 77-80 PMID28326376show ga
  • Alkaptonuria is disorder of tyrosine metabolism due to deficiency of homogentisic oxidase characterized by excretion of homogentisic acid in urine, deposition of oxidized homogensitate pigments in connective tissues and articular cartilages (ochronosis). The result is dark pigmentation and weakening of the tissues resulting in chronic inflammation and osteoarthritis. Management of alkaptonuric ochronic osteoarthritis is usually symptomatic and replacements have comparable outcomes to osteoarthritis in patients without ochronosis. I report a case of a patient with ochronosis of knee treated with total knee replacement and report operative pearls for surgery in this rare disorder.
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