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10.1097/COH.0000000000000283

http://scihub22266oqcxt.onion/10.1097/COH.0000000000000283
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C4947377!4947377!27023285
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suck abstract from ncbi

pmid27023285      Curr+Opin+HIV+AIDS 2016 ; 11 (4): 376-82
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  • Strategies to Target Non-T cell HIV Reservoirs #MMPMID27023285
  • Sacha JB; Ndhlovu LC
  • Curr Opin HIV AIDS 2016[Jul]; 11 (4): 376-82 PMID27023285show ga
  • Purpose: A central question for the HIV cure field is to determine new ways to target clinically relevant, latently and actively replicating HIV-infected cells beyond resting memory CD4+ T cells, particularly in anatomical areas of low drug penetrability. Recent findings: HIV eradication strategies being positioned for targeting HIV for extinction in the CD4 T cell compartment may also show promise in non-CD4 T cells reservoirs. Furthermore, several exciting novel therapeutic approaches specifically focused on HIV clearance from non-CD4 T cells populations are being developed. Summary: Although reservoir validity in these non-CD4 T cells continues to remain debated, this review will highlight recent advances and make an argument as to their clinical relevancy as we progress towards an HIV cure.
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