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Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Biomicrofluidics 2016 ; 10 (4): ä Nephropedia Template TP
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Introducing natural thermoplastic shellac to microfluidics: A green fabrication method for point-of-care devices #MMPMID27478525
Lausecker R; Badilita V; Gleißner U; Wallrabe U
Biomicrofluidics 2016[Jul]; 10 (4): ä PMID27478525show ga
We present a sustainable fabrication method for cheap point-of-care microfluidic systems, employing hot embossing of natural shellac as a key feature of an energy-efficient fabrication method that exclusively uses renewable materials as consumables. Shellac is a low-cost renewable biomaterial that features medium hydrophilicity (e.g., a water contact angle of ca. 73°) and a high chemical stability with respect to common solvents such as cyclohexane or toluene, rendering it an interesting candidate for low-cost microfluidics and a competitor to well-known systems such as paper-based or polydimethylsiloxane-based microfluidics. Moreover, its high replication accuracy for small features down to 30??m lateral feature size and its ability to form smooth surfaces (surface roughness Ra?=?29?nm) at low embossing temperatures (glass transition temperature Tg?=?42.2?°C) enable energy-efficient hot embossing of microfluidic structures. Proof-of-concept for the implementation of shellac hot embossing as a green fabrication method for microfluidic systems is demonstrated through the successful fabrication of a microfluidic test setup and the assessment of its resource consumption.