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10.1016/j.biomaterials.2016.06.010 http://scihub22266oqcxt.onion/10.1016/j.biomaterials.2016.06.010 C4939127!4939127!27336184     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Biomaterials 2016 ; 102 (ä): 120-9 Nephropedia Template TP {{tp|p=27336184|t=2016. Implantable Tissue-Engineered Blood Vessels from Human Induced Pluripotent Stem Cells |pdf=|usr=}}{{27336184}} gab.com Text Implantable Tissue-Engineered Blood Vessels from Human Induced Pluripotent Stem Cells JO: Biomaterials http://www.kidney.de/pget.php?&tw=1&pmid=27336184 #FOAvip Derivation of functional vascular smooth muscle cells (VSMCs) from human induced pluripotent stem cells (hiPSCs) to generate tissue-engineered blood vessels (TEBVs) holds great potential in treating patients with vascular diseases. Herein, hiPSCs were differentiated into alpha-smooth muscle actin (?-SMA) and calponin-positive VSMCs, which were seeded onto polymer scaffolds in bioreactors for vascular tissue growth. A functional TEBV with abundant collagenous matrix and sound mechanics resulted, which contained cells largely positive for ?-SMA and smooth muscle myosin heavy chain (SM-MHC). Moreover, when hiPSC-derived TEBV segments were implanted into nude rats as abdominal aorta interposition grafts, they remained unruptured and patent with active vascular remodeling, and showed no evidence of teratoma formation during a 2-week proof-of-principle study. Our studies represent the development of the first implantable TEBVs based on hiPSCs, and pave the way for developing autologous or allogeneic grafts for clinical use in patients with vascular disease. Twit Text FOAVip Implantable Tissue-Engineered Blood Vessels from Human Induced Pluripotent Stem Cells ????Biomaterials http://www.kidney.de/pget.php?&tw=1&pmid=27336184 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27336184 #FOAvip English Wikipedia <ref>{{Cite pmid|27336184}}</ref> Implantable Tissue-Engineered Blood Vessels from Human Induced Pluripotent Stem Cells #MMPMID27336184 Gui L; Dash BC; Luo J; Qin L; Zhao L; Yamamoto K; Hashimoto T; Wu H; Dardik A; Tellides G; Niklason LE; Qyang Y Biomaterials 2016[Sep]; 102 (ä): 120-9 PMID27336184show ga Derivation of functional vascular smooth muscle cells (VSMCs) from human induced pluripotent stem cells (hiPSCs) to generate tissue-engineered blood vessels (TEBVs) holds great potential in treating patients with vascular diseases. Herein, hiPSCs were differentiated into alpha-smooth muscle actin (?-SMA) and calponin-positive VSMCs, which were seeded onto polymer scaffolds in bioreactors for vascular tissue growth. A functional TEBV with abundant collagenous matrix and sound mechanics resulted, which contained cells largely positive for ?-SMA and smooth muscle myosin heavy chain (SM-MHC). Moreover, when hiPSC-derived TEBV segments were implanted into nude rats as abdominal aorta interposition grafts, they remained unruptured and patent with active vascular remodeling, and showed no evidence of teratoma formation during a 2-week proof-of-principle study. Our studies represent the development of the first implantable TEBVs based on hiPSCs, and pave the way for developing autologous or allogeneic grafts for clinical use in patients with vascular disease. äImplantable Tissue-Engineered Blood Vessels from Human Induced Pluripo(epmc).pdf DeepDyve Pubget Overpricing