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10.1111/nyas.13016 http://scihub22266oqcxt.onion/10.1111/nyas.13016 C4938003!4938003!27015419     free     free     free       Ann+N+Y+Acad+Sci 2016 ; 1370 (1): 82-96 Nephropedia Template TP {{tp|p=27015419|t=2016. Niche heterogeneity in the bone marrow |pdf=|usr=}}{{27015419}} gab.com Text Niche heterogeneity in the bone marrow JO: Ann N Y Acad Sci http://www.kidney.de/pget.php?&tw=1&pmid=27015419 #FOAvip In adult mammals, hematopoietic stem cells (HSCs) are defined by their abilities to self-renew and to differentiate to form all blood cell lineages. These rare multipotent cells occupy specific locations in the bone marrow microenvironment. The specific microenvironment regulating HSCs, commonly referred to as the niche, comprises multiple cell types whose exact contributions are under active investigation. Understanding cellular cross talk involving HSCs in the bone marrow microenvironment is of fundamental importance for harnessing therapies against benign and malignant blood diseases. In this review, we summarize and evaluate recent advances in our understanding of niche heterogeneity and its influence on HSC function. Twit Text FOAVip Niche heterogeneity in the bone marrow ????Ann N Y Acad Sci http://www.kidney.de/pget.php?&tw=1&pmid=27015419 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27015419 #FOAvip English Wikipedia <ref>{{Cite pmid|27015419}}</ref> Niche heterogeneity in the bone marrow #MMPMID27015419 Birbrair A; Frenette PS Ann N Y Acad Sci 2016[Apr]; 1370 (1): 82-96 PMID27015419show ga In adult mammals, hematopoietic stem cells (HSCs) are defined by their abilities to self-renew and to differentiate to form all blood cell lineages. These rare multipotent cells occupy specific locations in the bone marrow microenvironment. The specific microenvironment regulating HSCs, commonly referred to as the niche, comprises multiple cell types whose exact contributions are under active investigation. Understanding cellular cross talk involving HSCs in the bone marrow microenvironment is of fundamental importance for harnessing therapies against benign and malignant blood diseases. In this review, we summarize and evaluate recent advances in our understanding of niche heterogeneity and its influence on HSC function. äNiche heterogeneity in the bone marrow (epmc).pdf DeepDyve Pubget Overpricing