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10.1016/j.tibs.2016.04.010 http://scihub22266oqcxt.onion/10.1016/j.tibs.2016.04.010 C4930396!4930396!27236301     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Trends+Biochem+Sci 2016 ; 41 (7): 595-609 Nephropedia Template TP {{tp|p=27236301|t=2016. Catalytic DNA: Scope, Applications, and Biochemistry of Deoxyribozymes |pdf=|usr=}}{{27236301}} gab.com Text Catalytic DNA: Scope, Applications, and Biochemistry of Deoxyribozymes JO: Trends Biochem Sci http://www.kidney.de/pget.php?&tw=1&pmid=27236301 #FOAvip The discovery of natural RNA enzymes (ribozymes) prompted the pursuit of artificial DNA enzymes (deoxyribozymes) by in vitro selection methods. A key motivation is the conceptual and practical advantages of DNA relative to proteins and RNA. Early studies focused on RNA-cleaving deoxyribozymes, and more recent experiments have expanded the breadth of catalytic DNA to many other reactions. Including modified nucleotides has the potential to widen the scope of DNA enzymes even further. Practical applications of deoxyribozymes include their use as sensors for metal ions and small molecules. Structural studies of deoxyribozymes are just beginning; mechanistic experiments will surely follow. From the first report 21 years ago, the field of deoxyribozymes has promise for both fundamental and applied advances in chemistry, biology, and other disciplines. Twit Text FOAVip Catalytic DNA: Scope, Applications, and Biochemistry of Deoxyribozymes ????Trends Biochem Sci http://www.kidney.de/pget.php?&tw=1&pmid=27236301 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27236301 #FOAvip English Wikipedia <ref>{{Cite pmid|27236301}}</ref> Catalytic DNA: Scope, Applications, and Biochemistry of Deoxyribozymes #MMPMID27236301 Silverman SK Trends Biochem Sci 2016[Jul]; 41 (7): 595-609 PMID27236301show ga The discovery of natural RNA enzymes (ribozymes) prompted the pursuit of artificial DNA enzymes (deoxyribozymes) by in vitro selection methods. A key motivation is the conceptual and practical advantages of DNA relative to proteins and RNA. Early studies focused on RNA-cleaving deoxyribozymes, and more recent experiments have expanded the breadth of catalytic DNA to many other reactions. Including modified nucleotides has the potential to widen the scope of DNA enzymes even further. Practical applications of deoxyribozymes include their use as sensors for metal ions and small molecules. Structural studies of deoxyribozymes are just beginning; mechanistic experiments will surely follow. From the first report 21 years ago, the field of deoxyribozymes has promise for both fundamental and applied advances in chemistry, biology, and other disciplines. äCatalytic DNA: Scope, Applications, and Biochemistry of Deoxyribozymes(epmc).pdf DeepDyve Pubget Overpricing