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10.1161/STROKEAHA.116.012727

http://scihub22266oqcxt.onion/10.1161/STROKEAHA.116.012727
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suck abstract from ncbi


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pmid27197848
      Stroke 2016 ; 47 (7 ): 1933-5
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  • Endovascular Hypothermia in Acute Ischemic Stroke: Pilot Study of Selective Intra-Arterial Cold Saline Infusion #MMPMID27197848
  • Chen J ; Liu L ; Zhang H ; Geng X ; Jiao L ; Li G ; Coutinho JM ; Ding Y ; Liebeskind DS ; Ji X
  • Stroke 2016[Jul]; 47 (7 ): 1933-5 PMID27197848 show ga
  • BACKGROUND AND PURPOSE: We conducted a pilot feasibility and safety study of selective brain cooling with intra-arterial infusion of cold saline combined with endovascular reperfusion for acute ischemic stroke. METHODS: Patients with large-vessel occlusion within 8 hours after symptom onset were enrolled. All patients received intra-arterial recanalization combined with infusion of cold isotonic saline (4°C) in the ischemic territory through the angiographic catheter. RESULTS: Twenty-six patients underwent the procedure, which was technically successful in all. The temperature of ischemic cerebral tissue was decreased by at least 2°C during infusion of the cold solution, and systemic temperature was mildly reduced (maximum 0.3°C). No obvious complications related to intra-arterial hypothermia were observed. CONCLUSIONS: Selective brain cooling by intra-arterial infusion of cold saline combined with endovascular recanalization therapy in acute ischemic stroke seems feasible and safe.
  • |*Endovascular Procedures [MESH]
  • |Adult [MESH]
  • |Aged [MESH]
  • |Brain Ischemia/drug therapy/*therapy [MESH]
  • |Cold Temperature [MESH]
  • |Combined Modality Therapy [MESH]
  • |Feasibility Studies [MESH]
  • |Female [MESH]
  • |Fibrinolytic Agents/administration & dosage/therapeutic use [MESH]
  • |Humans [MESH]
  • |Hypothermia, Induced/*methods [MESH]
  • |Infusions, Intra-Arterial [MESH]
  • |Male [MESH]
  • |Middle Aged [MESH]
  • |Pilot Projects [MESH]
  • |Sodium Chloride/administration & dosage/*therapeutic use [MESH]


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