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10.1053/j.gastro.2016.03.006 http://scihub22266oqcxt.onion/10.1053/j.gastro.2016.03.006 C4924569!4924569!27003602     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Gastroenterology 2016 ; 151 (1): 120-129.e5 Nephropedia Template TP {{tp|p=27003602|t=2016. Administration of Antibiotics to Children Before Age 2 Years Increases Risk for Childhood Obesity |pdf=|usr=}}{{27003602}} gab.com Text Administration of Antibiotics to Children Before Age 2 Years Increases Risk for Childhood Obesity JO: Gastroenterology http://www.kidney.de/pget.php?&tw=1&pmid=27003602 #FOAvip Background & Aims: Childhood obesity is increasing and is associated with adult obesity. Antibiotics have been used to promote weight gain in livestock for several decades. Antibiotics are commonly prescribed for children, but it is not clear how exposure to antibiotics early in life affects risk for obesity. We performed a population-based cohort study to assess the association between antibiotic exposure before age 2 years and obesity at age 4 years. Methods: We performed a retrospective cohort study of 21,714 children in The Health Improvement Network ?a population-representative dataset of more than 10 million individuals derived from electronic medical records from 1995 through 2013 in the United Kingdom. Eligible subjects were registered within 3 months of birth with complete follow-up and height and weight were recorded within 12 months of their 4th birthday. Antibiotic exposure was assessed before age 2 years, and classified based on anti-anaerobic activity. The primary outcome was obesity at age 4 years. We performed logistic regression analyses, adjusting for maternal and sibling obesity, maternal diabetes, mode of delivery, socioeconomic status, year and country of birth, and urban dwelling. Results: In the cohort, 1306 of the children (6.4%) were obese at 4 years of age. Antibiotic exposure was associated with an increased risk of obesity at 4 years (odds ratio [OR]=1.21; 95% confidence interval [CI], 1.07?1.38). Odds ratios increased with repeated exposures: for 1?2 prescriptions, OR=1.07 (95% CI, 0.91?1.23); for 3?5 prescriptions, OR=1.41 (95% CI, 1.20?1.65); for 6 or more prescriptions, OR=1.47 (95% CI, 1.19?1.82). Antifungal agents were not associated with obesity (OR=0.81; 95% CI, 0.59?1.11). Conclusions: Administration of 3 or more courses of antibiotics before children reach an age of 2 years is associated with an increased risk of early childhood obesity. Twit Text FOAVip Administration of Antibiotics to Children Before Age 2 Years Increases Risk for Childhood Obesity ????Gastroenterology http://www.kidney.de/pget.php?&tw=1&pmid=27003602 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27003602 #FOAvip English Wikipedia <ref>{{Cite pmid|27003602}}</ref> Administration of Antibiotics to Children Before Age 2 Years Increases Risk for Childhood Obesity #MMPMID27003602 Scott FI; Horton DB; Mamtani R; Haynes K; Goldberg DS; Lee DY; Lewis JD Gastroenterology 2016[Jul]; 151 (1): 120-129.e5 PMID27003602show ga Background & Aims: Childhood obesity is increasing and is associated with adult obesity. Antibiotics have been used to promote weight gain in livestock for several decades. Antibiotics are commonly prescribed for children, but it is not clear how exposure to antibiotics early in life affects risk for obesity. We performed a population-based cohort study to assess the association between antibiotic exposure before age 2 years and obesity at age 4 years. Methods: We performed a retrospective cohort study of 21,714 children in The Health Improvement Network ?a population-representative dataset of more than 10 million individuals derived from electronic medical records from 1995 through 2013 in the United Kingdom. Eligible subjects were registered within 3 months of birth with complete follow-up and height and weight were recorded within 12 months of their 4th birthday. Antibiotic exposure was assessed before age 2 years, and classified based on anti-anaerobic activity. The primary outcome was obesity at age 4 years. We performed logistic regression analyses, adjusting for maternal and sibling obesity, maternal diabetes, mode of delivery, socioeconomic status, year and country of birth, and urban dwelling. Results: In the cohort, 1306 of the children (6.4%) were obese at 4 years of age. Antibiotic exposure was associated with an increased risk of obesity at 4 years (odds ratio [OR]=1.21; 95% confidence interval [CI], 1.07?1.38). Odds ratios increased with repeated exposures: for 1?2 prescriptions, OR=1.07 (95% CI, 0.91?1.23); for 3?5 prescriptions, OR=1.41 (95% CI, 1.20?1.65); for 6 or more prescriptions, OR=1.47 (95% CI, 1.19?1.82). Antifungal agents were not associated with obesity (OR=0.81; 95% CI, 0.59?1.11). Conclusions: Administration of 3 or more courses of antibiotics before children reach an age of 2 years is associated with an increased risk of early childhood obesity. äAdministration of Antibiotics to Children Before Age 2 Years Increases(epmc).pdf DeepDyve Pubget Overpricing