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10.3978/j.issn.2306-9759.2015.05.03 http://scihub22266oqcxt.onion/10.3978/j.issn.2306-9759.2015.05.03 C4923650!4923650 !27358880     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 251.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 251.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\27358880 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Stem+Cell+Investig 2015 ; 2 (ä): 12 Nephropedia Template TP {{tp|p=27358880 |t=2015. Interplay of retinal determination gene network with TGF-? signaling pathway in epithelial-mesenchymal transition |pdf=|usr=}}{{27358880 }} gab.com Text Interplay of retinal determination gene network with TGF- signaling pathway in epithelial-mesenchymal transition JO: Stem Cell Investig http://www.kidney.de/pget.php?&tw=1&pmid=27358880 #FOAvip As a fundamental event in the generation of tissues and organs during embryogenesis, the epithelial-mesenchymal transition (EMT) has also been implicated in cancer progression by its ability to alter the plasticity of epithelial cells to acquire invasive properties. Evidence is mounting that ectopic activation of transforming growth factors ? (TGF-?)/bone morphogenetic protein (BMP) superfamily members to enhance tumorigenesis and metastasis. In this respect, the Retinal Determination Gene Network (RDGN), which was identified to govern the normal initiation of the morphogenetic furrow in Drosophila, has now been found to be de-regulated in various types of cancers, and the key members of this network, DACH, SIX, and EYA, have emerged as novel co-regulators of TGF- signaling during EMT. Understanding the molecular mechanism by which RDGN regulates TGF-?/BMP signaling to influence EMT may lead to novel strategies for targeted therapies. Twit Text FOAVip Interplay of retinal determination gene network with TGF- signaling pathway in epithelial-mesenchymal transition ????Stem Cell Investig http://www.kidney.de/pget.php?&tw=1&pmid=27358880 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27358880 #FOAvip English Wikipedia <ref>{{Cite pmid|27358880 }}</ref> Interplay of retinal determination gene network with TGF-? signaling pathway in epithelial-mesenchymal transition #MMPMID27358880 Liu Y ; Kong D ; Wu H ; Yuan X ; Xu H ; Zhang C ; Wu G ; Wu K Stem Cell Investig 2015[]; 2 (ä): 12 PMID27358880 show ga As a fundamental event in the generation of tissues and organs during embryogenesis, the epithelial-mesenchymal transition (EMT) has also been implicated in cancer progression by its ability to alter the plasticity of epithelial cells to acquire invasive properties. Evidence is mounting that ectopic activation of transforming growth factors ? (TGF-?)/bone morphogenetic protein (BMP) superfamily members to enhance tumorigenesis and metastasis. In this respect, the Retinal Determination Gene Network (RDGN), which was identified to govern the normal initiation of the morphogenetic furrow in Drosophila, has now been found to be de-regulated in various types of cancers, and the key members of this network, DACH, SIX, and EYA, have emerged as novel co-regulators of TGF- signaling during EMT. Understanding the molecular mechanism by which RDGN regulates TGF-?/BMP signaling to influence EMT may lead to novel strategies for targeted therapies. äInterplay of retinal determination gene network with TGF-? signaling p(epmc).pdf DeepDyve Pubget Overpricing