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10.3978/j.issn.2306-9759.2014.07.01 http://scihub22266oqcxt.onion/10.3978/j.issn.2306-9759.2014.07.01 C4923514!4923514!27358861     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Stem+Cell+Investig 2014 ; 1 (ä): ä Nephropedia Template TP {{tp|p=27358861|t=2014. Regulatory factors of induced pluripotency: current status |pdf=|usr=}}{{27358861}} gab.com Text Regulatory factors of induced pluripotency: current status JO: Stem Cell Investig http://www.kidney.de/pget.php?&tw=1&pmid=27358861 #FOAvip Somatic cells can be reprogrammed to induced pluripotent stem cells (iPSCs) through enforced expression of four transcription factors [Oct4, Sox2, Klf4, and c-Myc (OSKM)]; however, the reprogramming efficiency is extremely low. This finding raises fundamental questions about the regulators that influence the change in epigenetic stability and endowment of dedifferentiation potential during reprogramming. Identification of such regulators is critical to removing the roadblocks impeding the efficient generation of safe iPSCs and their successful translation into clinical therapies. In this review, we summarize the current progress that has been made in understanding cellular reprogramming, with an emphasis on the molecular mechanisms of epigenetic regulators in induced pluripotency. Twit Text FOAVip Regulatory factors of induced pluripotency: current status ????Stem Cell Investig http://www.kidney.de/pget.php?&tw=1&pmid=27358861 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27358861 #FOAvip English Wikipedia <ref>{{Cite pmid|27358861}}</ref> Regulatory factors of induced pluripotency: current status #MMPMID27358861 Zhao W; Ning B; Qian C Stem Cell Investig 2014[]; 1 (ä): ä PMID27358861show ga Somatic cells can be reprogrammed to induced pluripotent stem cells (iPSCs) through enforced expression of four transcription factors [Oct4, Sox2, Klf4, and c-Myc (OSKM)]; however, the reprogramming efficiency is extremely low. This finding raises fundamental questions about the regulators that influence the change in epigenetic stability and endowment of dedifferentiation potential during reprogramming. Identification of such regulators is critical to removing the roadblocks impeding the efficient generation of safe iPSCs and their successful translation into clinical therapies. In this review, we summarize the current progress that has been made in understanding cellular reprogramming, with an emphasis on the molecular mechanisms of epigenetic regulators in induced pluripotency. äRegulatory factors of induced pluripotency: current status (epmc).pdf DeepDyve Pubget Overpricing