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10.1002/art.39614 http://scihub22266oqcxt.onion/10.1002/art.39614 C4920688!4920688 !26814428     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26814428 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Arthritis+Rheumatol 2016 ; 68 (7 ): 1711-20 Nephropedia Template TP {{tp|p=26814428 |t=2016. Trends in Long-Term Outcomes Among Patients With Antineutrophil Cytoplasmic Antibody-Associated Vasculitis With Renal Disease |pdf=|usr=}}{{26814428 }} gab.com Text Trends in Long-Term Outcomes Among Patients With Antineutrophil Cytoplasmic Antibody-Associated Vasculitis With Renal Disease JO: Arthritis Rheumatol http://www.kidney.de/pget.php?&tw=1&pmid=26814428 #FOAvip OBJECTIVE: It is still not clear how advances in the management of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) have impacted long-term outcomes. We undertook this study to examine changes over 25 years in long-term clinical outcomes, including the impact of renal function at diagnosis (a potential marker of time to disease detection) and the duration of cyclophosphamide use in AAV patients with renal involvement. METHODS: We included ANCA-positive patients with biopsy-proven AAV diagnosed between 1985 and 2009 who were followed up in the Glomerular Disease Collaborative Network inception cohort. Outcomes included the composite outcome of end-stage renal disease (ESRD) or death as well as relapse. Cox proportional hazards or competing risks regression models were adjusted for potential baseline confounders. RESULTS: Data from 554 patients were included in the analysis. There was a decreasing 5-year risk of ESRD or death over time (P?<?0.001 by log rank test for trend). After adjustment for baseline characteristics, the risk of relapse was similar across the time periods (P?=?0.45 by test for trend). Serum creatinine level at baseline was the only significant predictor of an increased risk of ESRD or death (hazard ratio 1.11 per 1 mg/dl of serum creatinine [95% confidence interval 1.04-1.18], P?=?0.002). CONCLUSION: In patients with renal disease secondary to AAV, over 25 years the risk of ESRD or death has decreased but the risk of relapse has not changed. A higher serum creatinine level at diagnosis is associated with a higher risk of ESRD or death, suggesting that earlier disease detection is potentially an important measure to improve outcomes in AAV. Twit Text FOAVip Trends in Long-Term Outcomes Among Patients With Antineutrophil Cytoplasmic Antibody-Associated Vasculitis With Renal Disease ????Arthritis Rheumatol http://www.kidney.de/pget.php?&tw=1&pmid=26814428 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26814428 #FOAvip English Wikipedia <ref>{{Cite pmid|26814428 }}</ref> Trends in Long-Term Outcomes Among Patients With Antineutrophil Cytoplasmic Antibody-Associated Vasculitis With Renal Disease #MMPMID26814428 Rhee RL ; Hogan SL ; Poulton CJ ; McGregor JA ; Landis JR ; Falk RJ ; Merkel PA Arthritis Rheumatol 2016[Jul]; 68 (7 ): 1711-20 PMID26814428 show ga OBJECTIVE: It is still not clear how advances in the management of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) have impacted long-term outcomes. We undertook this study to examine changes over 25 years in long-term clinical outcomes, including the impact of renal function at diagnosis (a potential marker of time to disease detection) and the duration of cyclophosphamide use in AAV patients with renal involvement. METHODS: We included ANCA-positive patients with biopsy-proven AAV diagnosed between 1985 and 2009 who were followed up in the Glomerular Disease Collaborative Network inception cohort. Outcomes included the composite outcome of end-stage renal disease (ESRD) or death as well as relapse. Cox proportional hazards or competing risks regression models were adjusted for potential baseline confounders. RESULTS: Data from 554 patients were included in the analysis. There was a decreasing 5-year risk of ESRD or death over time (P? |Adult [MESH] |Aged [MESH] |Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis/*complications/*drug therapy [MESH] |Cyclophosphamide/*therapeutic use [MESH] |Female [MESH] |Humans [MESH] |Immunosuppressive Agents/*therapeutic use [MESH] |Kidney Failure, Chronic/epidemiology/*etiology [MESH] |Male [MESH] |Middle Aged [MESH] |Risk Assessment [MESH] |Time Factors [MESH]Trends in Long-Term Outcomes Among Patients With Antineutrophil Cytopl(epmc).pdf DeepDyve Pubget Overpricing