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10.1111/bph.13505 http://scihub22266oqcxt.onion/10.1111/bph.13505 C4919578!4919578!27128025     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Br+J+Pharmacol 2016 ; 173 (14): 2182-94 Nephropedia Template TP {{tp|p=27128025|t=2016. Extracellular nicotinamide phosphoribosyltransferase, a new cancer metabokine |pdf=|usr=}}{{27128025}} gab.com Text Extracellular nicotinamide phosphoribosyltransferase, a new cancer metabokine JO: Br J Pharmacol http://www.kidney.de/pget.php?&tw=1&pmid=27128025 #FOAvip In this review, we focus on the secreted form of nicotinamide phosphoribosyltransferase (NAMPT); extracellular NAMPT (eNAMPT), also known as pre?B cell colony?enhancing factor or visfatin. Although intracellular NAMPT is a key enzyme in controlling NAD metabolism, eNAMPT has been reported to function as a cytokine, with many roles in physiology and pathology. Circulating eNAMPT has been associated with several metabolic and inflammatory disorders, including cancer. Because cytokines produced in the tumour micro?environment play an important role in cancer pathogenesis, in part by reprogramming cellular metabolism, future improvements in cancer immunotherapy will require a better understanding of the crosstalk between cytokine action and tumour biology. In this review, the knowledge of eNAMPT in cancer will be discussed, focusing on its immunometabolic function as a metabokine, its secretion, its mechanism of action and possible roles in the cancer micro?environment. Twit Text FOAVip Extracellular nicotinamide phosphoribosyltransferase, a new cancer metabokine ????Br J Pharmacol http://www.kidney.de/pget.php?&tw=1&pmid=27128025 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27128025 #FOAvip English Wikipedia <ref>{{Cite pmid|27128025}}</ref> Extracellular nicotinamide phosphoribosyltransferase, a new cancer metabokine #MMPMID27128025 Grolla AA; Travelli C; Genazzani AA; Sethi JK Br J Pharmacol 2016[Jul]; 173 (14): 2182-94 PMID27128025show ga In this review, we focus on the secreted form of nicotinamide phosphoribosyltransferase (NAMPT); extracellular NAMPT (eNAMPT), also known as pre?B cell colony?enhancing factor or visfatin. Although intracellular NAMPT is a key enzyme in controlling NAD metabolism, eNAMPT has been reported to function as a cytokine, with many roles in physiology and pathology. Circulating eNAMPT has been associated with several metabolic and inflammatory disorders, including cancer. Because cytokines produced in the tumour micro?environment play an important role in cancer pathogenesis, in part by reprogramming cellular metabolism, future improvements in cancer immunotherapy will require a better understanding of the crosstalk between cytokine action and tumour biology. In this review, the knowledge of eNAMPT in cancer will be discussed, focusing on its immunometabolic function as a metabokine, its secretion, its mechanism of action and possible roles in the cancer micro?environment. äExtracellular nicotinamide phosphoribosyltransferase, a new cancer met(epmc).pdf DeepDyve Pubget Overpricing