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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Am+J+Case+Rep
2016 ; 17
(ä): 340-6
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gab.com Text
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English Wikipedia
Clinical Spectrum and Management of Caustic Ingestion: A Case Series Presenting
Three Opposing Outcomes
#MMPMID27197994
Vezakis AI
; Pantiora EV
; Kontis EA
; Sakellariou V
; Theodorou D
; Gkiokas G
; Polydorou AA
; Fragulidis GP
Am J Case Rep
2016[May]; 17
(ä): 340-6
PMID27197994
show ga
BACKGROUND: Ingestion of caustic substances is a medical emergency in both the
adult and pediatric population and is associated with high morbidity and
mortality. The extent of injuries after ingestion of caustic substances depends
on the nature, amount, and concentration of the agent and on the exposure time.
Acutely, caustic substances may cause massive hemorrhage and gastrointestinal
tract perforation; the most markedly affected cases require urgent surgical
treatment. Patients surviving the initial event may present with aorto-enteric or
gastrocolic fistulae, esophageal strictures, dysphagia, and increased risk of
esophageal cancer as long term sequelae. CASE REPORT: The features of three cases
of caustic ingestion are reported to demonstrate significantly different
complaints presented at the emergency department. Two patients had free gastric
perforation, one at presentation, and one delayed. The third patient presented
with late severe strictures of the esophagus and pylorus. The outcomes of the
three patients are discussed in detail along with the most current management
strategies. CONCLUSIONS: Among adults, ingestion of caustic substances is usually
associated with more severe lesions due to the increased amount of ingested
substance, as compared with pediatric patients. The most serious presentation is
that of visceral perforation, most commonly of the stomach and rarely of the
esophagus. Management involves urgent resuscitation with correction of fluid and
electrolyte and acid-base abnormalities and immediate surgical exploration in
those patients with signs of perforation. Once the perioperative period is
managed successfully, the long-term results can be satisfactory. Managing of
strictures or else reconstructive procedures must be well timed to allow for
psychological and nutritional rehabilitation.