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10.1080/19491034.2016.1162933 http://scihub22266oqcxt.onion/10.1080/19491034.2016.1162933 C4916884!4916884!26963026     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Nucleus 2016 ; 7 (2): 167-86 Nephropedia Template TP {{tp|p=26963026|t=2016. Recent advances in understanding nuclear size and shape |pdf=|usr=}}{{26963026}} gab.com Text Recent advances in understanding nuclear size and shape JO: Nucleus http://www.kidney.de/pget.php?&tw=1&pmid=26963026 #FOAvip Size and shape are important aspects of nuclear structure. While normal cells maintain nuclear size within a defined range, altered nuclear size and shape are associated with a variety of diseases. It is unknown if altered nuclear morphology contributes to pathology, and answering this question requires a better understanding of the mechanisms that control nuclear size and shape. In this review, we discuss recent advances in our understanding of the mechanisms that regulate nuclear morphology, focusing on nucleocytoplasmic transport, nuclear lamins, the endoplasmic reticulum, the cell cycle, and potential links between nuclear size and size regulation of other organelles. We then discuss the functional significance of nuclear morphology in the context of early embryonic development. Looking toward the future, we review new experimental approaches that promise to provide new insights into mechanisms of nuclear size control, in particular microfluidic-based technologies, and discuss how altered nuclear morphology might impact chromatin organization and physiology of diseased cells. Twit Text FOAVip Recent advances in understanding nuclear size and shape ????Nucleus http://www.kidney.de/pget.php?&tw=1&pmid=26963026 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26963026 #FOAvip English Wikipedia <ref>{{Cite pmid|26963026}}</ref> Recent advances in understanding nuclear size and shape #MMPMID26963026 Mukherjee RN; Chen P; Levy DL Nucleus 2016[]; 7 (2): 167-86 PMID26963026show ga Size and shape are important aspects of nuclear structure. While normal cells maintain nuclear size within a defined range, altered nuclear size and shape are associated with a variety of diseases. It is unknown if altered nuclear morphology contributes to pathology, and answering this question requires a better understanding of the mechanisms that control nuclear size and shape. In this review, we discuss recent advances in our understanding of the mechanisms that regulate nuclear morphology, focusing on nucleocytoplasmic transport, nuclear lamins, the endoplasmic reticulum, the cell cycle, and potential links between nuclear size and size regulation of other organelles. We then discuss the functional significance of nuclear morphology in the context of early embryonic development. Looking toward the future, we review new experimental approaches that promise to provide new insights into mechanisms of nuclear size control, in particular microfluidic-based technologies, and discuss how altered nuclear morphology might impact chromatin organization and physiology of diseased cells. äRecent advances in understanding nuclear size and shape (epmc).pdf DeepDyve Pubget Overpricing