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10.1136/bmjopen-2016-011315

http://scihub22266oqcxt.onion/10.1136/bmjopen-2016-011315
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suck abstract from ncbi


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pmid27324714
      BMJ+Open 2016 ; 6 (6 ): e011315
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  • ?-Adrenoreceptor agonists in the management of pain associated with renal colic: a systematic review #MMPMID27324714
  • Tabner AJ ; Johnson GD ; Fakis A ; Surtees J ; Lennon RI
  • BMJ Open 2016[Jun]; 6 (6 ): e011315 PMID27324714 show ga
  • OBJECTIVES: To determine whether ?-adrenoreceptor agonists are effective analgesics for patients with renal colic through a systematic review of the literature. SETTING: Adult emergency departments or acute assessment units. PARTICIPANTS: Human participants with proven or suspected renal colic. INTERVENTIONS: ?-adrenoreceptor agonists. OUTCOME MEASURES: Primary: level of pain at 30?min following administration of the ?-agonist. Secondary: level of pain at various time points following ?-agonist administration; length of hospital stay; analgesic requirement; stone presence, size and position; degree of hydronephrosis. RESULTS: 256 records were screened and 4 identified for full-text review. No articles met the inclusion criteria. CONCLUSIONS AND IMPLICATIONS: There is no evidence to support or refute the proposed use of ?-agonists for analgesia in patients with renal colic. Given the biological plausibility and existing literature base, clinical trials investigating the use of ?-adrenoreceptor agonists in the acute setting for treatment of the pain associated with renal colic are recommended. TRIAL REGISTRATION NUMBER: CRD42015016266.
  • |Adrenergic beta-Agonists/*therapeutic use [MESH]
  • |Analgesics/*therapeutic use [MESH]
  • |Emergency Medical Services [MESH]
  • |Humans [MESH]
  • |Pain Management [MESH]
  • |Pain/etiology [MESH]
  • |Renal Colic/*drug therapy [MESH]


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