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10.1186/s13054-016-1320-7 http://scihub22266oqcxt.onion/10.1186/s13054-016-1320-7 C4916531!4916531!27329228     free     free     free       Crit+Care 2016 ; 20 (ä): ä Nephropedia Template TP {{tp|p=27329228|t=2016. Antibiotic strategies in the era of multidrug resistance |pdf=|usr=}}{{27329228}} gab.com Text Antibiotic strategies in the era of multidrug resistance JO: Crit Care http://www.kidney.de/pget.php?&tw=1&pmid=27329228 #FOAvip The rapid emergence and dissemination of antibiotic-resistant microorganisms in ICUs worldwide threaten adequate antibiotic coverage of infected patients in this environment. The causes of this problem are multifactorial, but the core issues are clear: the emergence of antibiotic resistance is highly correlated with selective pressure resulting from inappropriate use of these drugs. Because a significant increase in mortality is observed when antibiotic therapy is delayed in infected ICU patients, initial therapy should be broad enough to cover all likely pathogens. Receipt of unnecessary prolonged broad-spectrum antibiotics, however, should be avoided. Local microbiologic data are extremely important to predict the type of resistance that may be present for specific causative bacteria, as is prior antibiotic exposure, and antibiotic choices should thus be made at an individual patient level. Twit Text FOAVip Antibiotic strategies in the era of multidrug resistance ????Crit Care http://www.kidney.de/pget.php?&tw=1&pmid=27329228 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27329228 #FOAvip English Wikipedia <ref>{{Cite pmid|27329228}}</ref> Antibiotic strategies in the era of multidrug resistance #MMPMID27329228 Karam G; Chastre J; Wilcox MH; Vincent JL Crit Care 2016[]; 20 (ä): ä PMID27329228show ga The rapid emergence and dissemination of antibiotic-resistant microorganisms in ICUs worldwide threaten adequate antibiotic coverage of infected patients in this environment. The causes of this problem are multifactorial, but the core issues are clear: the emergence of antibiotic resistance is highly correlated with selective pressure resulting from inappropriate use of these drugs. Because a significant increase in mortality is observed when antibiotic therapy is delayed in infected ICU patients, initial therapy should be broad enough to cover all likely pathogens. Receipt of unnecessary prolonged broad-spectrum antibiotics, however, should be avoided. Local microbiologic data are extremely important to predict the type of resistance that may be present for specific causative bacteria, as is prior antibiotic exposure, and antibiotic choices should thus be made at an individual patient level. äAntibiotic strategies in the era of multidrug resistance (epmc).pdf DeepDyve Pubget Overpricing