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10.1016/j.gde.2015.12.005

http://scihub22266oqcxt.onion/10.1016/j.gde.2015.12.005
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C4914422!4914422!26821363
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suck abstract from ncbi

pmid26821363      Curr+Opin+Genet+Dev 2016 ; 37 (ä): 46-50
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  • Systematic approaches to identify functional lncRNAs #MMPMID26821363
  • Alcid EA; Tsukiyama T
  • Curr Opin Genet Dev 2016[Apr]; 37 (ä): 46-50 PMID26821363show ga
  • Long noncoding RNAs (lncRNAs) were discovered in eukaryotes more than thirty years ago [1]. Recent advances in genomics have led to the discovery that lncRNAs are transcribed pervasively across the genome [2?5]. There are an increasing number of reports that identify lncRNAs whose expression is modulated during cell differentiation or in disease states. However, biological functions for the vast majority of them are yet to be determined. Here, we propose two ways to identify lncRNAs that have biological functions: To identify lncRNAs with dedicated preinitiation complexes (PICs), and to focus on those whose transcription is highly regulated.
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