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10.1039/c6cc02764d

http://scihub22266oqcxt.onion/10.1039/c6cc02764d
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C4912020!4912020!27157466
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suck abstract from ncbi


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pmid27157466      Chem+Commun+(Camb) 2016 ; 52 (43): 6997-7000
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  • Quantum Dot ? NanoLuc Bioluminescence Resonance Energy Transfer Enables Tumor Imaging and Lymph Node Mapping In Vivo #MMPMID27157466
  • Kamkaew A; Sun H; England CG; Cheng L; Liu Z; Cai W
  • Chem Commun (Camb) 2016[May]; 52 (43): 6997-7000 PMID27157466show ga
  • A small luciferase protein (Nluc) was conjugated to QDs as a bioluminescence resonance energy transfer (BRET) pair. The conjugate showed 76% BRET efficiency and lymph node mapping was successfully performed. cRGD peptide was conjugated to QD-Nluc for tumor targeting. The self-illuminating QD-Nluc showed excellent energy transfer in a living system and offered optimal tumor-to-background ratio (>85).
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