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http://scihub22266oqcxt.onion/ C4911189!4911189!27331198     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Guo+Ji+Fang+She+Yi+Xue+He+Yi+Xue+Za+Zhi 2016 ; 40 (2): 91-9 Nephropedia Template TP {{tp|p=27331198|t=2016. Ionizing Radiation Induces HMGB1 Cytoplasmic Translocation and Extracellular Release |pdf=|usr=}}{{27331198}} gab.com Text Ionizing Radiation Induces HMGB1 Cytoplasmic Translocation and Extracellular Release JO: Guo Ji Fang She Yi Xue He Yi Xue Za Zhi http://www.kidney.de/pget.php?&tw=1&pmid=27331198 #FOAvip Objective: A nucleosomal protein, HMGB1, can be secreted by activated immune cells or passively released by dying cells, thereby amplifying rigorous inflammatory responses. In this study we aimed to test the possibility that ionizing radiation similarly induces cytoplasmic HMGB1 translocation and extracellular release. Method: Human skin fibroblast (GM0639) and bronchial epithelial (16HBE) cells and animals (rats) were exposed to X-ray radiation, and HMGB1 translocation and release were assessed by immunocytochemistry and immunoassay, respectively. Results: At a wide dose range (4.0 ? 12.0 Gy), X-ray radiation induced a dramatic cytoplasmic HMGB1 translocation, and triggered a time- and dose-dependent HMGB1 release both in vitro and in vivo. The radiation-mediated HMGB1 release was associated with noticeable chromosomal DNA damage and loss of cell viability. Conclusion: radiation induces HMGB1 cytoplasmic translocation and extracellular release through active secretion and passive leakage processes. Twit Text FOAVip Ionizing Radiation Induces HMGB1 Cytoplasmic Translocation and Extracellular Release ????Guo Ji Fang She Yi Xue He Yi Xue Za Zhi http://www.kidney.de/pget.php?&tw=1&pmid=27331198 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27331198 #FOAvip English Wikipedia <ref>{{Cite pmid|27331198}}</ref> Ionizing Radiation Induces HMGB1 Cytoplasmic Translocation and Extracellular Release #MMPMID27331198 Wang L; He L; Bao G; He X; Fan S; Wang H Guo Ji Fang She Yi Xue He Yi Xue Za Zhi 2016[Mar]; 40 (2): 91-9 PMID27331198show ga Objective: A nucleosomal protein, HMGB1, can be secreted by activated immune cells or passively released by dying cells, thereby amplifying rigorous inflammatory responses. In this study we aimed to test the possibility that ionizing radiation similarly induces cytoplasmic HMGB1 translocation and extracellular release. Method: Human skin fibroblast (GM0639) and bronchial epithelial (16HBE) cells and animals (rats) were exposed to X-ray radiation, and HMGB1 translocation and release were assessed by immunocytochemistry and immunoassay, respectively. Results: At a wide dose range (4.0 ? 12.0 Gy), X-ray radiation induced a dramatic cytoplasmic HMGB1 translocation, and triggered a time- and dose-dependent HMGB1 release both in vitro and in vivo. The radiation-mediated HMGB1 release was associated with noticeable chromosomal DNA damage and loss of cell viability. Conclusion: radiation induces HMGB1 cytoplasmic translocation and extracellular release through active secretion and passive leakage processes. äIonizing Radiation Induces HMGB1 Cytoplasmic Translocation and Extrace(epmc).pdf DeepDyve Pubget Overpricing