Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1016/j.celrep.2016.05.033 http://scihub22266oqcxt.onion/10.1016/j.celrep.2016.05.033 C4909540!4909540!27264173     free     free     free Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 261.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 261.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 261.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 261.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 261.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 261.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Cell+Rep 2016 ; 15 (11): 2510-23 Nephropedia Template TP {{tp|p=27264173|t=2016. The action of Discoidin Domain Receptor 2 in basal tumor cells and stromal Cancer Associated Fibroblasts is critical for breast cancer metastasis |pdf=|usr=}}{{27264173}} gab.com Text The action of Discoidin Domain Receptor 2 in basal tumor cells and stromal Cancer Associated Fibroblasts is critical for breast cancer metastasis JO: Cell Rep http://www.kidney.de/pget.php?&tw=1&pmid=27264173 #FOAvip High level of collagen deposition in human and mouse breast tumors are associated with poor outcome due to increased local invasion and distant metastases. Using a genetic approach we show, in mice, that the action of the fibrillar collagen receptor, discoidin domain receptor 2 (DDR2) in both tumor and tumor stromal cells is critical for breast cancer metastasis, yet does not affect primary tumor growth. In tumor cells, DDR2 in basal epithelial cells regulates collective invasion of tumor organoids. In stromal cancer-associated fibroblasts (CAFs) DDR2 is critical for extracellular matrix production and organization of collagen fibers. The action of DDR2 in CAFs also enhances tumor cell collective invasion through a pathway distinct from the tumor cell-intrinsic function of DDR2. This work identifies DDR2 as a potential therapeutic target that controls breast cancer metastases through its action in both tumor cells and tumor stromal cells at the primary tumor site. Twit Text FOAVip The action of Discoidin Domain Receptor 2 in basal tumor cells and stromal Cancer Associated Fibroblasts is critical for breast cancer metastasis ????Cell Rep http://www.kidney.de/pget.php?&tw=1&pmid=27264173 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27264173 #FOAvip English Wikipedia <ref>{{Cite pmid|27264173}}</ref> The action of Discoidin Domain Receptor 2 in basal tumor cells and stromal Cancer Associated Fibroblasts is critical for breast cancer metastasis #MMPMID27264173 Corsa CAS; Brenot A; Grither WR; Van Hove S; Loza AJ; Zhang K; Ponik SM; Liu Y; DeNardo DG; Eliceiri KW; Keely PJ; Longmore GD Cell Rep 2016[Jun]; 15 (11): 2510-23 PMID27264173show ga High level of collagen deposition in human and mouse breast tumors are associated with poor outcome due to increased local invasion and distant metastases. Using a genetic approach we show, in mice, that the action of the fibrillar collagen receptor, discoidin domain receptor 2 (DDR2) in both tumor and tumor stromal cells is critical for breast cancer metastasis, yet does not affect primary tumor growth. In tumor cells, DDR2 in basal epithelial cells regulates collective invasion of tumor organoids. In stromal cancer-associated fibroblasts (CAFs) DDR2 is critical for extracellular matrix production and organization of collagen fibers. The action of DDR2 in CAFs also enhances tumor cell collective invasion through a pathway distinct from the tumor cell-intrinsic function of DDR2. This work identifies DDR2 as a potential therapeutic target that controls breast cancer metastases through its action in both tumor cells and tumor stromal cells at the primary tumor site. äThe action of Discoidin Domain Receptor 2 in basal tumor cells and str(epmc).pdf DeepDyve Pubget Overpricing