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10.1177/0271678X15622047 http://scihub22266oqcxt.onion/10.1177/0271678X15622047 C4908626!4908626 !26690495     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=26690495 &cmd=llinks): Failed to open stream: HTTP request failed! 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Ultra-fast magnetic resonance encephalography of physiological brain activity - Glymphatic pulsation mechanisms? |pdf=|usr=}}{{26690495 }} gab.com Text Ultra-fast magnetic resonance encephalography of physiological brain activity - Glymphatic pulsation mechanisms JO: J Cereb Blood Flow Metab http://www.kidney.de/pget.php?&tw=1&pmid=26690495 #FOAvip The theory on the glymphatic convection mechanism of cerebrospinal fluid holds that cardiac pulsations in part pump cerebrospinal fluid from the peri-arterial spaces through the extracellular tissue into the peri-venous spaces facilitated by aquaporin water channels. Since cardiac pulses cannot be the sole mechanism of glymphatic propulsion, we searched for additional cerebrospinal fluid pulsations in the human brain with ultra-fast magnetic resonance encephalography. We detected three types of physiological mechanisms affecting cerebral cerebrospinal fluid pulsations: cardiac, respiratory, and very low frequency pulsations. The cardiac pulsations induce a negative magnetic resonance encephalography signal change in peri-arterial regions that extends centrifugally and covers the brain in ?1?Hz cycles. The respiratory ?0.3?Hz pulsations are centripetal periodical pulses that occur dominantly in peri-venous areas. The third type of pulsation was very low frequency (VLF 0.001-0.023?Hz) and low frequency (LF 0.023-0.73?Hz) waves that both propagate with unique spatiotemporal patterns. Our findings using critically sampled magnetic resonance encephalography open a new view into cerebral fluid dynamics. Since glymphatic system failure may precede protein accumulations in diseases such as Alzheimer's dementia, this methodological advance offers a novel approach to image brain fluid dynamics that potentially can enable early detection and intervention in neurodegenerative diseases. Twit Text FOAVip Ultra-fast magnetic resonance encephalography of physiological brain activity - Glymphatic pulsation mechanisms ????J Cereb Blood Flow Metab http://www.kidney.de/pget.php?&tw=1&pmid=26690495 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26690495 #FOAvip English Wikipedia <ref>{{Cite pmid|26690495 }}</ref> Ultra-fast magnetic resonance encephalography of physiological brain activity - Glymphatic pulsation mechanisms? #MMPMID26690495 Kiviniemi V ; Wang X ; Korhonen V ; Keinänen T ; Tuovinen T ; Autio J ; LeVan P ; Keilholz S ; Zang YF ; Hennig J ; Nedergaard M J Cereb Blood Flow Metab 2016[Jun]; 36 (6 ): 1033-45 PMID26690495 show ga The theory on the glymphatic convection mechanism of cerebrospinal fluid holds that cardiac pulsations in part pump cerebrospinal fluid from the peri-arterial spaces through the extracellular tissue into the peri-venous spaces facilitated by aquaporin water channels. Since cardiac pulses cannot be the sole mechanism of glymphatic propulsion, we searched for additional cerebrospinal fluid pulsations in the human brain with ultra-fast magnetic resonance encephalography. We detected three types of physiological mechanisms affecting cerebral cerebrospinal fluid pulsations: cardiac, respiratory, and very low frequency pulsations. The cardiac pulsations induce a negative magnetic resonance encephalography signal change in peri-arterial regions that extends centrifugally and covers the brain in ?1?Hz cycles. The respiratory ?0.3?Hz pulsations are centripetal periodical pulses that occur dominantly in peri-venous areas. The third type of pulsation was very low frequency (VLF 0.001-0.023?Hz) and low frequency (LF 0.023-0.73?Hz) waves that both propagate with unique spatiotemporal patterns. Our findings using critically sampled magnetic resonance encephalography open a new view into cerebral fluid dynamics. Since glymphatic system failure may precede protein accumulations in diseases such as Alzheimer's dementia, this methodological advance offers a novel approach to image brain fluid dynamics that potentially can enable early detection and intervention in neurodegenerative diseases. |Adult [MESH] |Brain/blood supply [MESH] |Cerebrospinal Fluid/physiology [MESH] |Cerebrovascular Circulation/physiology [MESH] |Female [MESH] |Humans [MESH] |Magnetic Resonance Imaging/*methods [MESH] |Male [MESH] |Neuroimaging/*methods [MESH] |Pulsatile Flow/*physiology [MESH]Ultra-fast magnetic resonance encephalography of physiological brain a(epmc).pdf DeepDyve Pubget Overpricing