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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Hepat+Mon
2016 ; 16
(5
): e35532
Nephropedia Template TP
gab.com Text
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Twit Text #
English Wikipedia
Hepatitis C Virus (HCV) Prevalence in Special Populations and Associated Risk
Factors: A Report From a Tertiary Hospital
#MMPMID27313634
Onyekwere CA
; O Ogbera A
; Olusola Dada A
; O Adeleye O
; O Dosunmu A
; Akinbami AA
; Osikomaiya B
; Hameed O
Hepat Mon
2016[May]; 16
(5
): e35532
PMID27313634
show ga
BACKGROUND: With the advent of highly effective anti-hepatitis C virus (HCV)
drugs, efforts to identify infected cases, high-risk groups, and associated risk
factors have become the focus of current control measures. OBJECTIVES: To
determine the prevalence of the HCV antibody among diabetics and patients with
lymphoproliferative disorders (LPD) who presented to the outpatient clinics of a
university hospital and its associated risk factors. PATIENTS AND METHODS:
Consecutively consenting patients who had been previously diagnosed with diabetes
mellitus and LPD at the outpatient department of the Lagos State University
teaching hospital were recruited. A case record form was used to extract their
demographics and physical examination findings as well as any risk factors for
HCV infection; blood was also drawn to run a serological assay for the HCV
antibody. All data were collated and analyzed using the Statistical Package for
the Social Sciences version 20. Student T-test, Chi square, and logistic
regression were some of the inferential statistics used in addition to
descriptive statistics. RESULTS: In all, 438 patients (405 diabetics and 33
patients with LPD) were recruited. Their ages ranged from 17 - 87 years with a
mean + Standard deviation of 59.61 + 11.859 years. The prevalence of hepatitis C
among the diabetic subgroup was 0.7%, while the antibody was present in 9.1% of
the LPD patients. The occurrence of the HCV antibody was, however, not
significantly associated with age, sex, educational level, or marital status (P >
0.05). Having multiple sexual partners was identified as the only significant
risk factor for hepatitis C (OR = 9.148; P = 0.017). CONCLUSIONS: This survey
suggested that a higher HCV prevalence exists in this population than is
currently reported in the general population, and having sex with multiple
partners was a risk factor for HCV infection.