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10.1016/j.vetpar.2010.05.019 http://scihub22266oqcxt.onion/10.1016/j.vetpar.2010.05.019 C4907795!4907795 !20615616     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=20615616 &cmd=llinks): Failed to open stream: HTTP request failed! 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A protozoal-associated epizootic impacting marine wildlife: mass-mortality of southern sea otters (Enhydra lutris nereis) due to Sarcocystis neurona infection |pdf=|usr=}}{{20615616 }} gab.com Text A protozoal-associated epizootic impacting marine wildlife: mass-mortality of southern sea otters (Enhydra lutris nereis) due to Sarcocystis neurona infection JO: Vet Parasitol http://www.kidney.de/pget.php?&tw=1&pmid=20615616 #FOAvip During April 2004, 40 sick and dead southern sea otters (Enhydra lutris nereis) were recovered over 18km of coastline near Morro Bay, California. This event represented the single largest monthly spike in mortality ever recorded during 30 years of southern sea otter stranding data collection. Because of the point-source nature of the event and clinical signs consistent with severe, acute neurological disease, exposure to a chemical or marine toxin was initially considered. However, detailed postmortem examinations revealed lesions consistent with an infectious etiology, and further investigation confirmed the protozoan parasite Sarcocystis neurona as the underlying cause. Tissues from 94% of examined otters were PCR-positive for S. neurona, based on DNA amplification and sequencing at the ITS-1 locus, and 100% of tested animals (n=14) had elevated IgM and IgG titers to S. neurona. Evidence to support the point-source character of this event include the striking spatial and temporal clustering of cases and detection of high concentrations of anti-S. neurona IgM in serum of stranded animals. Concurrent exposure to the marine biotoxin domoic acid may have enhanced susceptibility of affected otters to S. neurona and exacerbated the neurological signs exhibited by stranded animals. Other factors that may have contributed to the severity of this epizootic include a large rainstorm that preceded the event and an abundance of razor clams near local beaches, attracting numerous otters close to shore within the affected area. This is the first report of a localized epizootic in marine wildlife caused by apicomplexan protozoa. Twit Text FOAVip A protozoal-associated epizootic impacting marine wildlife: mass-mortality of southern sea otters (Enhydra lutris nereis) due to Sarcocystis neurona infection ????Vet Parasitol http://www.kidney.de/pget.php?&tw=1&pmid=20615616 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=20615616 #FOAvip English Wikipedia <ref>{{Cite pmid|20615616 }}</ref> A protozoal-associated epizootic impacting marine wildlife: mass-mortality of southern sea otters (Enhydra lutris nereis) due to Sarcocystis neurona infection #MMPMID20615616 Miller MA ; Conrad PA ; Harris M ; Hatfield B ; Langlois G ; Jessup DA ; Magargal SL ; Packham AE ; Toy-Choutka S ; Melli AC ; Murray MA ; Gulland FM ; Grigg ME Vet Parasitol 2010[Sep]; 172 (3-4 ): 183-94 PMID20615616 show ga During April 2004, 40 sick and dead southern sea otters (Enhydra lutris nereis) were recovered over 18km of coastline near Morro Bay, California. This event represented the single largest monthly spike in mortality ever recorded during 30 years of southern sea otter stranding data collection. Because of the point-source nature of the event and clinical signs consistent with severe, acute neurological disease, exposure to a chemical or marine toxin was initially considered. However, detailed postmortem examinations revealed lesions consistent with an infectious etiology, and further investigation confirmed the protozoan parasite Sarcocystis neurona as the underlying cause. Tissues from 94% of examined otters were PCR-positive for S. neurona, based on DNA amplification and sequencing at the ITS-1 locus, and 100% of tested animals (n=14) had elevated IgM and IgG titers to S. neurona. Evidence to support the point-source character of this event include the striking spatial and temporal clustering of cases and detection of high concentrations of anti-S. neurona IgM in serum of stranded animals. Concurrent exposure to the marine biotoxin domoic acid may have enhanced susceptibility of affected otters to S. neurona and exacerbated the neurological signs exhibited by stranded animals. Other factors that may have contributed to the severity of this epizootic include a large rainstorm that preceded the event and an abundance of razor clams near local beaches, attracting numerous otters close to shore within the affected area. This is the first report of a localized epizootic in marine wildlife caused by apicomplexan protozoa. |*Epidemics [MESH] |*Sarcocystis/genetics [MESH] |Animals [MESH] |Antibodies, Protozoan/blood [MESH] |Aquatic Organisms/*parasitology [MESH] |Bivalvia/chemistry [MESH] |Brain/parasitology [MESH] |California [MESH] |DNA, Ribosomal Spacer/genetics [MESH] |Kainic Acid/analogs & derivatives/analysis [MESH] |Muscle, Skeletal/chemistry/parasitology [MESH] |Neuromuscular Depolarizing Agents/analysis [MESH] |Otters/*parasitology [MESH] |Pacific Ocean [MESH]A protozoal-associated epizootic impacting marine wildlife: mass-morta(epmc).pdf DeepDyve Pubget Overpricing