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2013 ; 34
(7
): 1308-18
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
CNS-immune reconstitution inflammatory syndrome in the setting of HIV infection,
part 2: discussion of neuro-immune reconstitution inflammatory syndrome with and
without other pathogens
#MMPMID22790252
Post MJ
; Thurnher MM
; Clifford DB
; Nath A
; Gonzalez RG
; Gupta RK
; Post KK
AJNR Am J Neuroradiol
2013[Jul]; 34
(7
): 1308-18
PMID22790252
show ga
While the previous review of CNS-IRIS in the HIV-infected patient on highly
active antiretroviral therapy (Part 1) dealt with an overview of the biology,
pathology, and neurologic presentation of this condition and a discussion of the
atypical imaging findings in PML-IRIS and cryptococcal meningitis-IRIS due to the
robust inflammatory response, the current review (Part 2) discusses the imaging
findings in other commonly encountered organisms seen in association with
CNS-IRIS, namely, VZV, CMV, HIV, Candida organisms, Mycobacterium tuberculosis,
and Toxoplasma gondii. Also described is the imaging appearance of CNS-IRIS when
not associated with a particular organism. Recognition of these imaging findings
will give credence to the diagnosis of CNS-IRIS and will allow the clinician to
institute changes in medical management, if necessary, so that immune
reconstitution and improved patient outcome can occur with time.