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10.1080/23723556.2015.1090048

http://scihub22266oqcxt.onion/10.1080/23723556.2015.1090048
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C4905394!4905394!27308625
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suck abstract from ncbi


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pmid27308625      Mol+Cell+Oncol 2016 ; 3 (2): ä
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  • Breaking a paradigm: IL-6/STAT3 signaling suppresses metastatic prostate cancer upon ARF expression #MMPMID27308625
  • Culig Z; Pencik J; Merkel O; Kenner L
  • Mol Cell Oncol 2016[Mar]; 3 (2): ä PMID27308625show ga
  • Interleukin 6 (IL-6)/signal transducer and activator of transcription 3 (STAT3) signaling is considered to have important oncogenic functions in prostate cancer (PCa). However, a recent study highlighted the central role of IL-6/STAT3 signaling in regulation of the ARF?MDM2?p53 senescence axis. This reversal of the postulated oncogenic properties of IL-6/STAT3 signaling in PCa has important therapeutic implications.
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