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10.1080/23723556.2014.998900

http://scihub22266oqcxt.onion/10.1080/23723556.2014.998900
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suck abstract from ncbi


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pmid27308519
      Mol+Cell+Oncol 2015 ; 2 (4 ): e998900
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  • Unraveling the therapeutic potential of the LncRNA-dependent noncanonical Hedgehog pathway in cancer #MMPMID27308519
  • Xing Z ; Lin C ; Yang L
  • Mol Cell Oncol 2015[Oct]; 2 (4 ): e998900 PMID27308519 show ga
  • Acquired resistance to Hedgehog pathway inhibitors has been reported in the clinical setting and upregulation of noncanonical Hedgehog signaling is one of the major underlying mechanisms behind this resistance. As demonstrated in our recent study, greater clinical efficacy might be achieved by focusing on downstream targets of the chemokine-activated noncanonical Hedgehog signaling pathway such as BCAR4 and phospho-GLI2 (Ser149).
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