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10.1080/23723556.2014.999513

http://scihub22266oqcxt.onion/10.1080/23723556.2014.999513
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C4905357!4905357!27308523
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suck abstract from ncbi

pmid27308523      Mol+Cell+Oncol 2015 ; 2 (4): ä
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  • Taspase 1: A protease with many biological surprises #MMPMID27308523
  • Niizuma H; Cheng EH; Hsieh JJ
  • Mol Cell Oncol 2015[Oct]; 2 (4): ä PMID27308523show ga
  • Taspase 1 (TASP1) cleaves the mixed-lineage leukemia (MLL) and transcription factor (TF) IIA families of nuclear proteins to orchestrate various biological processes. TASP1 is not a classical oncogene, but assists in cell proliferation and permits oncogenic initiation through cleavage of MLL and TFIIA. TASP1 is thus better classified as a ?non-oncogene addiction? protease, and targeting TASP1 offers a novel and attractive anticancer therapeutic strategy.
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