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10.4161/23723548.2014.970072

http://scihub22266oqcxt.onion/10.4161/23723548.2014.970072
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C4905236!4905236!27308404
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suck abstract from ncbi


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pmid27308404      Mol+Cell+Oncol 2015 ; 2 (1): ä
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  • The PBAF chromatin remodeling complex represses transcription and promotes rapid repair at DNA double-strand breaks #MMPMID27308404
  • Kakarougkas A; Downs JA; Jeggo PA
  • Mol Cell Oncol 2015[Jan]; 2 (1): ä PMID27308404show ga
  • Transcription in the vicinity of DNA double-strand breaks (DSBs) is suppressed via a process involving ataxia telangiectasia mutated protein (ATM) and H2AK119 ubiquitylation.1 We discuss recent findings that components of the Polybromo and Brahma-related gene 1 (BRG1)-associated factor (PBAF) remodeling complex and the polycomb repressive complex (PRC1/2) are also required.2 Failure to activate transcriptional suppression impedes a rapid DSB repair process.
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