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10.4161/23723556.2014.980660

http://scihub22266oqcxt.onion/10.4161/23723556.2014.980660
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suck abstract from ncbi


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pmid27308443
      Mol+Cell+Oncol 2015 ; 2 (2 ): e980660
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  • Harnessing the nuclear receptor PPAR? to inhibit the growth of lung adenocarcinoma by rewiring metabolic circuitries #MMPMID27308443
  • Yenerall P ; Kittler R
  • Mol Cell Oncol 2015[Apr]; 2 (2 ): e980660 PMID27308443 show ga
  • Altered metabolism and nuclear receptor activity have been reported in various cancer types. Here, we discuss our recent finding that the metabolic state of lung adenocarcinoma cells expressing the nuclear receptor peroxisome proliferator-activated receptor gamma (PPAR?) can be modulated by thiazolidinediones, culminating in accumulation of reactive oxygen species and decreased proliferation.
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