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10.4161/23723548.2014.970951

http://scihub22266oqcxt.onion/10.4161/23723548.2014.970951
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C4904883!4904883!27308422
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suck abstract from ncbi

pmid27308422      Mol+Cell+Oncol 2015 ; 2 (2): ä
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  • TRIM32 is a novel negative regulator of p53 #MMPMID27308422
  • Liu J; Zhu Y; Hu W; Feng Z
  • Mol Cell Oncol 2015[Apr]; 2 (2): ä PMID27308422show ga
  • To ensure proper function, the tumor suppressor p53 is tightly regulated through different post-translational modifications, particularly ubiquitination. Recently, TRIM32 was identified as a p53-regulated gene and an E3 ubiquitin ligase of p53. Thus, TRIM32 and p53 form a novel auto-regulatory negative feedback loop for p53 regulation in cells.
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