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2016 ; 95
(19
): e3648
Nephropedia Template TP
gab.com Text
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Factors Affecting the Referral Time to Nephrologists in Patients With Chronic
Kidney Disease: A Prospective Cohort Study in Korea
#MMPMID27175688
Lee J
; Lee JP
; An JN
; Kim SG
; Kim YL
; Yang CW
; Kang SW
; Kim NH
; Kim YS
; Oh YK
; Lim CS
Medicine (Baltimore)
2016[May]; 95
(19
): e3648
PMID27175688
show ga
Timely referral to nephrologists is important for improving clinical outcomes and
reducing costs during transition periods. We evaluated the impact of patients'
demographic, clinical, and social health characteristics on referral time.A total
of 1744 CKD patients who started maintaining dialysis were enrolled in a Korean
prospective cohort. The early referral (ER) and late referral group (LR) were
defined as patients who were referred to a nephrologist more than or less than 1
year prior to dialysis initiation, respectively.A total of 1088 patients (62.3%)
were in the ER, and 656 patients (37.6%) were in the LR. Among the patients in
the LR, 398 patients (60.7%) were referred within the 3 months prior to the start
of dialysis (ultralate referral group [ULR]). The ER was younger at the time of
referral than the LR; however, the ER was older at the start of dialysis.
Patients with diabetes or hypertension as the cause of kidney disease were more
common in the LR, whereas patients with glomerulonephritis, females, and
nonsmokers were more common in the ER. The ER had more well-controlled blood
pressure, lower phosphorus levels, and higher hemoglobin levels at the start of
dialysis. Congestive heart failure (CHF) was more common in the LR. In the
multivariate analysis, male sex (odds ratio [OR] 1.465, 95% confidence interval
[CI] 1.034-2.076), underlying kidney disease (diabetes mellitus [OR 1.507, 95% CI
1.057-2.148] and hypertension [OR 1.995, 95% CI 1.305-3.051]), occupation
(mechanician [OR 2.975, 95% CI 1.445-6.125], laborer [OR 3.209, 95% CI
1.405-7.327], and farmer [OR 5.147, 95% CI 2.217-11.953]), CHF (OR 2.152, 95% CI
1.543-3.000), and ambulatory status (assisted-walks, OR 2.072, 95% CI
1.381-3.111) were proved as the independent risk factor for late
referral.Patients with hypertensive or diabetic kidney disease are referred later
than those with glomerulonephritis. Male patients with physically active
occupations exhibiting CHF and restricted ambulation were associated with a late
referral. Considering the various factors associated with late referral, efforts
to increase early referrals should be emphasized, particularly in patients with
hypertension, diabetes, or congestive heart failure.
|*Time-to-Treatment
[MESH]
|Adult
[MESH]
|Age Factors
[MESH]
|Aged
[MESH]
|Diabetic Nephropathies/complications
[MESH]
|Female
[MESH]
|Heart Failure/complications
[MESH]
|Humans
[MESH]
|Hypertension/complications
[MESH]
|Male
[MESH]
|Middle Aged
[MESH]
|Multivariate Analysis
[MESH]
|Nephrology/*statistics & numerical data
[MESH]
|Occupations
[MESH]
|Prospective Studies
[MESH]
|Referral and Consultation/*statistics & numerical data
[MESH]