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10.4103/0971-9784.173030

http://scihub22266oqcxt.onion/10.4103/0971-9784.173030
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C4900375!4900375!26750680
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suck abstract from ncbi

pmid26750680      Ann+Card+Anaesth 2016 ; 19 (1): 89-96
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  • Management of refractory hypoxemia #MMPMID26750680
  • Mehta C; Mehta Y
  • Ann Card Anaesth 2016[Jan]; 19 (1): 89-96 PMID26750680show ga
  • Mechanical ventilation remains the cornerstone in the management of severe acute respiratory failure. Acute respiratory distress syndrome (ARDS) is the most common cause of respiratory failure. It is associated with substantial mortality, and unmanageable refractory hypoxemia remains the most feared clinical possibility. If hypoxemia persists despite application of lung protective ventilation, additional therapies including inhaled vasodilators, prone positioning, recruitment maneuvers, high-frequency oscillatory ventilation, neuromuscular blockade (NMB), and extracorporeal membrane oxygenation may be needed. NMB and prone ventilation are modalities that have been clearly linked to reduced mortality in ARDS. Rescue therapies pose a clinical challenge requiring a precarious balance of risks and benefits, as well as, in-depth knowledge of therapeutic limitations.
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