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10.1021/acs.orglett.6b00911

http://scihub22266oqcxt.onion/10.1021/acs.orglett.6b00911
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C4900145!4900145!27218884
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suck abstract from ncbi


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pmid27218884      Org+Lett 2016 ; 18 (11): 2572-5
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  • Single-Electron Transmetalation: Protecting-Group-Independent Synthesis of Secondary Benzylic Alcohol Derivatives via Photoredox/Nickel Dual Catalysis #MMPMID27218884
  • Karimi-Nami R; Tellis JC; Molander GA
  • Org Lett 2016[Jun]; 18 (11): 2572-5 PMID27218884show ga
  • Protecting-group-independent cross-coupling of ?-alkoxyalkyl- and ?-acyloxyalkyltrifluoroborates with aryl and heteroaryl bromides is achieved through application of photoredox/nickel dual catalysis. Reactions occur under exceptionally mild conditions, with outstanding functional group compatibility and excellent observed tolerance of heteroarenes. This method offers expedient access to protected secondary benzylic alcohol motifs bearing benzyl, pivaloyl, and N,N-diisopropylcarbamoyl protecting groups.
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