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2016 ; 2016
(ä): 4386127
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A Systematic Review of Point of Care Testing for Chlamydia trachomatis, Neisseria
gonorrhoeae, and Trichomonas vaginalis
#MMPMID27313440
Herbst de Cortina S
; Bristow CC
; Joseph Davey D
; Klausner JD
Infect Dis Obstet Gynecol
2016[]; 2016
(ä): 4386127
PMID27313440
show ga
Objectives. Systematic review of point of care (POC) diagnostic tests for
sexually transmitted infections: Chlamydia trachomatis (CT), Neisseria
gonorrhoeae (NG), and Trichomonas vaginalis (TV). Methods. Literature search on
PubMed for articles from January 2010 to August 2015, including original research
in English on POC diagnostics for sexually transmitted CT, NG, and/or TV.
Results. We identified 33 publications with original research on POC diagnostics
for CT, NG, and/or TV. Thirteen articles evaluated test performance, yielding at
least one test for each infection with sensitivity and specificity ?90%. Each
infection also had currently available tests with sensitivities <60%. Three
articles analyzed cost effectiveness, and five publications discussed
acceptability and feasibility. POC testing was acceptable to both providers and
patients and was also demonstrated to be cost effective. Fourteen proof of
concept articles introduced new tests. Conclusions. Highly sensitive and specific
POC tests are available for CT, NG, and TV, but improvement is possible. Future
research should focus on acceptability, feasibility, and cost of POC testing.
While pregnant women specifically have not been studied, the results available in
nonpregnant populations are encouraging for the ability to test and treat women
in antenatal care to prevent adverse pregnancy and neonatal outcomes.