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10.1016/j.copbio.2016.03.015 http://scihub22266oqcxt.onion/10.1016/j.copbio.2016.03.015 C4899244!4899244!27042975     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Curr+Opin+Biotechnol 2016 ; 39 (ä): 120-5 Nephropedia Template TP {{tp|p=27042975|t=2016. Single-cell states versus single-cell atlases?two classes of heterogeneity that differ in meaning and method |pdf=|usr=}}{{27042975}} gab.com Text Single-cell states versus single-cell atlases two classes of heterogeneity that differ in meaning and method JO: Curr Opin Biotechnol http://www.kidney.de/pget.php?&tw=1&pmid=27042975 #FOAvip Recent advances have created new opportunities to dissect cellular heterogeneity at the ?omics level. The enthusiasm for deep single-cell profiling has obscured a discussion of different types of heterogeneity and the most-appropriate techniques for studying each type. Here, I distinguish heterogeneity in regulation from heterogeneity in lineage. Snapshots of lineage heterogeneity provide a cell atlas that catalogs cellular diversity within complex tissues. Profiles of regulatory heterogeneity seek to interrogate one lineage deeply to capture an ensemble of single-cell states. Single-cell atlases require molecular signatures from many cells at a throughput afforded by mass cytometry-, microfluidic-, and microencapsulation-based methods. Single-cell states are more dependent on time, microenvironment, and low-abundance transcripts, emphasizing in situ methods that stress depth of profiling and quantitative accuracy. Twit Text FOAVip Single-cell states versus single-cell atlases two classes of heterogeneity that differ in meaning and method ????Curr Opin Biotechnol http://www.kidney.de/pget.php?&tw=1&pmid=27042975 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27042975 #FOAvip English Wikipedia <ref>{{Cite pmid|27042975}}</ref> Single-cell states versus single-cell atlases?two classes of heterogeneity that differ in meaning and method #MMPMID27042975 Janes KA Curr Opin Biotechnol 2016[Jun]; 39 (ä): 120-5 PMID27042975show ga Recent advances have created new opportunities to dissect cellular heterogeneity at the ?omics level. The enthusiasm for deep single-cell profiling has obscured a discussion of different types of heterogeneity and the most-appropriate techniques for studying each type. Here, I distinguish heterogeneity in regulation from heterogeneity in lineage. Snapshots of lineage heterogeneity provide a cell atlas that catalogs cellular diversity within complex tissues. Profiles of regulatory heterogeneity seek to interrogate one lineage deeply to capture an ensemble of single-cell states. Single-cell atlases require molecular signatures from many cells at a throughput afforded by mass cytometry-, microfluidic-, and microencapsulation-based methods. Single-cell states are more dependent on time, microenvironment, and low-abundance transcripts, emphasizing in situ methods that stress depth of profiling and quantitative accuracy. äSingle-cell states versus single-cell atlases?two classes of heterogen(epmc).pdf DeepDyve Pubget Overpricing